Design and Synthesis of New Immonium??Type Coupling Reagents

…, M Abdul??Ghani, F Albericio

Index: El-Faham, Ayman; Khattab, Sherine N.; Abdul-Ghani, Mohamed; Albericio, Fernando European Journal of Organic Chemistry, 2006 , # 6 p. 1563 - 1573

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Citation Number: 17

Abstract

Abstract A new family of immonium-type coupling reagents is described here. The differences in the carbocation skeletons of these reagents can be correlated with differences in stability and thus reactivity. The dihydroimidazole derivatives are highly unstable to air, whereas the salts derived from dimethylamine are the most stable and the pyrrolidino derivatives are of intermediate stability. These results should be taken into account mainly ...