LL-37 GKE trifluoroacetate salt

• 常用名: LL-37 GKE trifluoroacetate salt
• 英文名: LL-37 GKE trifluoroacetate salt
• CAS号: 913736-92-2
• 分子量: 2613.11
• 密度: 1.4±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₁₉H₂₀₂N₃₈O₂₈
• 熔点: N/A
• 闪点: N/A

LL-37 GKE trifluoroacetate salt用途

LL-37 GKE是LL-37的活性结构域。LL-37 GKE具有抗菌活性,在抗生素方面具有潜在的应用[1][2]。

LL-37 GKE trifluoroacetate salt名称

• 英文名: LL-37 GKE trifluoroacetate salt

LL-37 GKE trifluoroacetate salt生物活性

• 描述: LL-37 GKE是LL-37的活性结构域。LL-37 GKE具有抗菌活性,在抗生素方面具有潜在的应用[1][2]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Sigurdardottir T, et al. In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37. Antimicrob Agents Chemother. 2006 Sep;50(9):2983-9.

  [2]. Ringstad L, et al. Effects of single amino acid substitutions on peptide interaction with lipid membranes and bacteria–variants of GKE21, an internal sequence from human LL-37[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2010, 354(1-3): 65-71.

LL-37 GKE trifluoroacetate salt物理化学性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₁₁₉H₂₀₂N₃₈O₂₈
• 分子量: 2613.11
• 精确质量: 2611.555176
• LogP: -2.41
• InChIKey: XYNOBEXPWSIAKM-URRJLKHLSA-N
• SMILES: CCC(C)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)CN)C(C)CC)C(C)C)C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)O)C(C)C.O=C(O)C(F)(F)F
• 折射率: 1.647

LL-37 GKE trifluoroacetate salt英文别名

• Glycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparaginyl-L-leucy l-L-valyl-L-prolyl-L-arginine
• L-Arginine, glycyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparag inyl-L-leucyl-L-valyl-L-prolyl-