(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮

更新时间:2023-01-15 21:57:15

(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮结构式
(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮结构式
品牌特惠专场
常用名 (R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮 英文名 (7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone
CAS号 877676-50-1 分子量 268.743
密度 1.2±0.1 g/cm3 沸点 492.1±40.0 °C at 760 mmHg
分子式 C12H17ClN4O 熔点 N/A
MSDS N/A 闪点 251.4±27.3 °C

 名称

中文名 (7R)-2-氯-7-乙基-7,8-二氢-5-甲基-8-(1-甲基乙基)-6(5H)-蝶啶酮
英文名 (7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pter idinone
英文别名 更多

 物理化学性质

密度 1.2±0.1 g/cm3
沸点 492.1±40.0 °C at 760 mmHg
分子式 C12H17ClN4O
分子量 268.743
闪点 251.4±27.3 °C
精确质量 268.109100
PSA 49.33000
LogP 0.82
蒸汽压 0.0±1.2 mmHg at 25°C
折射率 1.541
储存条件 2-8°C,保存于惰性气体中

 安全信息

海关编码 2933990090

 合成线路

~84%

(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮结构式

(R)-2-氯-7-乙基-8-...

877676-50-1

文献:BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2009/19205 A1, 2009 ; Location in patent: Page/Page column 14 ;

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(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮结构式

(R)-2-氯-7-乙基-8-...

877676-50-1

文献:Bowers, Simeon; Truong, Anh P.; Ye, Michael; Aubele, Danielle L.; Sealy, Jennifer M.; Neitz, R. Jeffrey; Hom, Roy K.; Chan, Wayman; Dappen, Michael S.; Galemmo Jr., Robert A.; Konradi, Andrei W.; Sham, Hing L.; Zhu, Yong L.; Beroza, Paul; Tonn, George; Zhang, Heather; Hoffman, Jennifer; Motter, Ruth; Fauss, Donald; Tanaka, Pearl; Bova, Michael P.; Ren, Zhao; Tam, Danny; Ruslim, Lany; Baker, Jeanne; Pandya, Deepal; Diep, Linnea; Fitzgerald, Kent; Artis, Dean R.; Anderson, John P.; Bergeron, Marcelle Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2743 - 2749

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(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮结构式

(R)-2-氯-7-乙基-8-...

877676-50-1

文献:SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD. Patent: US2012/184543 A1, 2012 ; Title/Abstract Full Text Show Details Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co. Ltd. Patent: EP2481739 A1, 2012 ;

 海关

海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 英文别名

(R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one
(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone
(7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pteridinone
2-chloro-7,8-dimethyl-3-quinolinecarbaldehyde
2-chloro-7,8-dimethyl-3-quinolinecarboxaldehyde
2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-(7R)-6(5H)-pteridinone
(7R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7H-pteridin-6-one
2-Chloro-7,8-dimethylquinoline-3-carboxaldehyde
(R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one
6(5H)-Pteridinone, 2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-, (7R)-