877676-50-1

• 常用中文名：(R)-2-氯-7-乙基-8-异丙基-5-甲基-7,8-二氢蝶啶-6(5H)-酮
• 常用英文名：(7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone
• CAS号：877676-50-1
• 分子式：C₁₂H₁₇ClN₄O
• 分子量：268.743
• 发布时间：2018-12-28 12:40:20
• 更新时间：2025-08-25 13:25:22

名称

• 中文名: (7R)-2-氯-7-乙基-7,8-二氢-5-甲基-8-(1-甲基乙基)-6(5H)-蝶啶酮
• 英文名: (7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pter idinone
• 英文别名: (R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one; (7R)-2-Chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-6(5H)-pteridinone; (7R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-6(5H)-pteridinone; 2-chloro-7,8-dimethyl-3-quinolinecarbaldehyde; 2-chloro-7,8-dimethyl-3-quinolinecarboxaldehyde; 2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-(7R)-6(5H)-pteridinone; (7R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7H-pteridin-6-one; 2-Chloro-7,8-dimethylquinoline-3-carboxaldehyde; (R)-2-chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one; 6(5H)-Pteridinone, 2-chloro-7-ethyl-7,8-dihydro-5-methyl-8-(1-methylethyl)-, (7R)-

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 492.1±40.0 °C at 760 mmHg
• 分子式: C₁₂H₁₇ClN₄O
• 分子量: 268.743
• 闪点: 251.4±27.3 °C
• 精确质量: 268.109100
• PSA: 49.33000
• LogP: 0.82
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.541
• 储存条件: 2-8°C，保存于惰性气体中

安全

• 海关编码: 2933990090

合成路线

889877-77-4 616-38-6 ~84% 877676-50-1

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: WO2009/19205 A1, 2009 ; Location in patent: Page/Page column 14 ;

512-56-1 889877-77-4 ~% 877676-50-1

文献：Bowers, Simeon; Truong, Anh P.; Ye, Michael; Aubele, Danielle L.; Sealy, Jennifer M.; Neitz, R. Jeffrey; Hom, Roy K.; Chan, Wayman; Dappen, Michael S.; Galemmo Jr., Robert A.; Konradi, Andrei W.; Sham, Hing L.; Zhu, Yong L.; Beroza, Paul; Tonn, George; Zhang, Heather; Hoffman, Jennifer; Motter, Ruth; Fauss, Donald; Tanaka, Pearl; Bova, Michael P.; Ren, Zhao; Tam, Danny; Ruslim, Lany; Baker, Jeanne; Pandya, Deepal; Diep, Linnea; Fitzgerald, Kent; Artis, Dean R.; Anderson, John P.; Bergeron, Marcelle Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2743 - 2749

889877-77-4 80-48-8 ~% 877676-50-1

文献：SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD. Patent: US2012/184543 A1, 2012 ; Title/Abstract Full Text Show Details Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co. Ltd. Patent: EP2481739 A1, 2012 ;

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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%