灰叶草素, 羟基鱼藤素结构式
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常用名 | 灰叶草素, 羟基鱼藤素 | 英文名 | Tephrosin |
|---|---|---|---|---|
| CAS号 | 76-80-2 | 分子量 | 410.417 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 623.4±55.0 °C at 760 mmHg | |
| 分子式 | C23H22O7 | 熔点 | 198° (218-220°) | |
| MSDS | 美版 | 闪点 | 219.3±25.0 °C | |
| 符号 |
GHS09 |
信号词 | Warning |
灰叶草素, 羟基鱼藤素用途Tephrosin 是一种天然类胡萝卜素,具有较强的抗肿瘤活性。Tephrosin 通过诱导受体内化来诱导 EGFR 和 ErbB2 的降解。 |
| 中文名 | 灰叶草素, 羟基鱼藤素 |
|---|---|
| 英文名 | tephrosin |
| 英文别名 | 更多 |
| 描述 | Tephrosin 是一种天然类胡萝卜素,具有较强的抗肿瘤活性。Tephrosin 通过诱导受体内化来诱导 EGFR 和 ErbB2 的降解。 |
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| 相关类别 | |
| 体外研究 | 用tephrosin(0-10μM)处理HT-29细胞抑制EGFR,ErbB2和ErbB3的配体诱导和组成型磷酸化,并同时抑制下游信号分子如Akt和Erk1/2丝裂原活化蛋白激酶的活化。(MAPK)[1]。 |
| 参考文献 |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 623.4±55.0 °C at 760 mmHg |
| 熔点 | 198° (218-220°) |
| 分子式 | C23H22O7 |
| 分子量 | 410.417 |
| 闪点 | 219.3±25.0 °C |
| 精确质量 | 410.136566 |
| PSA | 83.45000 |
| LogP | 4.48 |
| 外观性状 | 黄色粉末 |
| 蒸汽压 | 0.0±1.9 mmHg at 25°C |
| 折射率 | 1.614 |
| 储存条件 | ?20°C |
| 灰叶草素, 羟基鱼藤素上游产品 0 | |
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| 灰叶草素, 羟基鱼藤素下游产品 1 | |
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[Rotenoids from Derris trifoliata].
Zhong Yao Cai 30(6) , 660-2, (2007) Five rotenoids named dehydrodeguelin, dehydrorotenone, 12a-hydroxy rotenone, tephrosin and 12alphabeta-hydroxyrot-2'-enonic acid were isolated from aerial parts of Derris trifoliata. All these compoun... |
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Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.
J. Chromatogr. A. 1178(1-2) , 101-7, (2008) Both analytical and preparative high-speed counter-current chromatography (HSCCC) were used to isolate and separate chemical bioactive constituents from the seeds of Millettia pachycarpa Benth, a famo... |
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Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.
Pest Manag. Sci. 59(10) , 1159-61, (2003) A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 microg ml(-1) at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera:... |
| Tephrosin |
| Toxicarol |
| (7aR,13aR)-7a-Hydroxy-9,10-dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one |
| 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)- |
| 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)- |
| Hydroxydeguelin |
| (7aR-cis)-13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one |
| 3H-[1]Benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aH)-one, 13,13a-dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR,13aR)- |
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CAS号522-17-8