AMG-076

• 常用名: AMG-076
• 英文名: AMG-076
• CAS号: 693823-79-9
• 分子量: 462.54800
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₃F₃N₂O₂
• 熔点: N/A
• 闪点: N/A

AMG-076用途

AMG-076 is a potent, selective, non-peptide antagonist of MCHR1 (Melanin-concentrating hormone receptor 1) with binding IC50 of 0.6 nM, with dramatically reduced hERG liability (IC50>5 uM).

AMG-076名称

• 英文名: 1-[2-[(4aR,11R,11aS)-11-methyl-9-(trifluoromethyl)-1,3,4,4a,5,6,11,11a-octahydropyrido[4,3-b]carbazol-2-yl]ethyl]cyclohexane-1-carboxylic acid

AMG-076物理化学性质

• 分子式: C₂₆H₃₃F₃N₂O₂
• 分子量: 462.54800
• 精确质量: 462.24900
• PSA: 56.33000
• LogP: 6.14750
• InChIKey: WAOZNBXSEVIAGX-MBOZVWFJSA-N
• SMILES: CC1c2c([nH]c3ccc(C(F)(F)F)cc23)CC2CCN(CCC3(C(=O)O)CCCCC3)CC21

AMG-076英文别名

• UNII-HX4T7JEV3D
• AMG-076 free base
• AMG 076