(3AR,4R,5R,6AS)-六氢-5-羟基-4-[(1E,3R)-3-羟基-4-(3-三氟甲基)苯氧基-1-丁烯基]-2H-环戊并[B]呋喃-2-酮

• 常用名: (3AR,4R,5R,6AS)-六氢-5-羟基-4-[(1E,3R)-3-羟基-4-(3-三氟甲基)苯氧基-1-丁烯基]-2H-环戊并[B]呋喃-2-酮
• 英文名: Fluprostenol Lactone Diol
• CAS号: 53872-60-9
• 分子量: 372.336
• 密度: 1.4±0.1 g/cm3
• 沸点: 520.6±50.0 °C at 760 mmHg
• 分子式: C₁₈H₁₉F₃O₅
• 熔点: N/A
• 闪点: 268.6±30.1 °C

名称

• 中文名: (+)-(3aR,4R,5r,6aS)-六氢-5-羟基-4-[(1E,3R)-3-羟基-4-(3-三氟甲基)苯氧基-1-丁烯基]-2H-环戊并[b]呋喃-2-酮
• 英文名: (3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
• 中文别名: 2H-环戊并[B]呋喃-2-酮,六氢-5-羟基-4-[(1E,3R)-3-羟基-4-[3-(三氟甲基)苯氧基]-1-丁烯-1-基]-,(3AR,4R,5R,6AS)- | (+)-(3AR,4R,5R,6AS)-六氢-5-羟基-4-[(1E,3R)-3-羟基-4-(3-三氟甲基)苯氧基-1-丁烯基]-2H-环戊并[B]呋喃-2-酮 | 曲沃前列素中间体

物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 520.6±50.0 °C at 760 mmHg
• 分子式: C₁₈H₁₉F₃O₅
• 分子量: 372.336
• 闪点: 268.6±30.1 °C
• 精确质量: 372.118469
• PSA: 75.99000
• LogP: 1.05
• InChIKey: XYSPYIAAWRUEML-UHFFFAOYSA-N
• SMILES: O=C1CC2C(CC(O)C2C=CC(O)COc2cccc(C(F)(F)F)c2)O1
• 蒸汽压: 0.0±1.4 mmHg at 25°C
• 折射率: 1.583
• 储存条件: -20°C

安全信息

• 危害码 (欧洲): Xn

英文别名

• Travoprost Intermediate
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aS,4R,5R,6aR)-
• (3aR,4R,5R,6aS)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
• (3aR,4R,5R,6aS)-5-Hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one
• (3aR,4R,5R,6aS)-5-hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-one
• (3aR,4R,5R,6aS)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
• (3aS,4R,5R,6aR)-5-Hydroxy-4-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}hexahydro-2H-cyclopenta[b]furan-2-one
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aR,4R,5R,6aS)-