ReAsH-EDT2

• 常用名: ReAsH-EDT2
• 英文名: ReAsH-EDT2
• CAS号: 438226-89-2
• 分子量: 545.38300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₃As₂NO₃S₄
• 熔点: N/A
• 闪点: N/A

ReAsH-EDT2用途

ReAsH-EDT2是一种标记蛋白质的红色荧光染料。ReAsH-EDT2是一种膜透性双砷化合物,与四环素序列共价结合,从而使蛋白质成像。ReAsH-EDT2可用于蛋白质定位和贩运。(λex=530 nm,λem=592 nm)[1][2]。

ReAsH-EDT2名称

• 英文名: 4,6-bis(1,3,2-dithiarsolan-2-yl)-7-hydroxyphenoxazin-3-one

ReAsH-EDT2生物活性

• 描述: ReAsH-EDT2是一种标记蛋白质的红色荧光染料。ReAsH-EDT2是一种膜透性双砷化合物,与四环素序列共价结合,从而使蛋白质成像。ReAsH-EDT2可用于蛋白质定位和贩运。(λex=530 nm,λem=592 nm)[1][2]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 带有GyrB.FGFR1KD的ReAsH-EDT2标签。TC可出现红色荧光。
• 参考文献:

  [1]. Adams SR, et, al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34.

  [2]. Perdios L, et, al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv Biol Regul. 2016 Jan;60:6-13.

ReAsH-EDT2物理化学性质

• 分子式: C₁₆H₁₃As₂NO₃S₄
• 分子量: 545.38300
• 精确质量: 544.82100
• PSA: 164.53000
• LogP: 2.34880
• InChIKey: UNIBJWQHKWCMGJ-UHFFFAOYSA-N
• SMILES: O=c1ccc2nc3ccc(O)c([As]4SCCS4)c3oc-2c1[As]1SCCS1

ReAsH-EDT2靶点实验

查看更多实验

实验名称：Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP cataly... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 7 External Id：CHEMBL4121953

实验名称：Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 1 External Id：CHEMBL4121935

实验名称：Inhibition of His6-tagged human wild-type HePTP catalytic domain at 1 uM using pNPP a... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 7 External Id：CHEMBL4121952

实验名称：Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP cataly... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 7 External Id：CHEMBL4121949

实验名称：Inhibition of His6-tagged human wild-type PTP catalytic domain at 500 nM using pNPP a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4121950

实验名称：Inhibition of allosterically sensitized mutant form of His6-tagged human FAP1 catalyt... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 13 External Id：CHEMBL4121963

实验名称：Inhibition of allosterically sensitized mutant form of His6-tagged human SHP1 catalyt... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 6 External Id：CHEMBL4121961

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ReAsH-EDT2英文别名

• Lumio Red
• ReAsH-EDT2
• 3H-Phenoxazin-3-one,4,6-di-1,3,2-dithiarsolan-2-yl-7-hydroxy
• 4,6-Di-1,3,2-dithiarsolan-2-yl-7-hydroxy-3H-phenoxazin-3-one