阿托伐他汀钙三水合物结构式
|
常用名 | 阿托伐他汀钙三水合物 | 英文名 | atorvastatin calcium trihydrate |
|---|---|---|---|---|
| CAS号 | 344423-98-9 | 分子量 | 1209.388 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C66H74CaF2N4O13 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
阿托伐他汀钙三水合物用途Atorvastatin is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia. |
| 中文名 | 阿托伐他汀钙三水合物 |
|---|---|
| 英文名 | atorvastatin calcium trihydrate |
| 中文别名 | 阿托伐他汀钙水合物 |
| 英文别名 | 更多 |
| 分子式 | C66H74CaF2N4O13 |
|---|---|
| 分子量 | 1209.388 |
| 精确质量 | 1208.484619 |
| PSA | 256.93000 |
| LogP | 9.91090 |
| 外观性状 | 固体;White to Almost white powder to crystal |
| 储存条件 | 室温，干燥 |
| 水溶解性 | Very slightly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
| 符号 |
GHS07, GHS08 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H319-H360D |
| 警示性声明 | P201-P280-P305 + P351 + P338-P308 + P313-P337 + P313 |
| 危害码 (欧洲) | T |
| 风险声明 (欧洲) | 61-36 |
| 安全声明 (欧洲) | 53-26-45 |
| 危险品运输编码 | NONH for all modes of transport |
|
Statins demonstrate a broad anti-cytomegalovirus activity in vitro in ganciclovir-susceptible and resistant strains.
J. Med. Virol. 87(1) , 141-53, (2014) Vasculoprotective and cholesterol-lowering properties are hallmarks of statins. Recently, statins have been found to exhibit antiviral activity. Little is known about the potential of statins against ... |
|
|
Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
Drug Metab. Pharmacokinet. 30(2) , 198-204, (2015) Since drug-drug interaction (DDI) can affect organic anion-transporting polypeptide (OATP) and cause clinical events, prediction of such DDI is important in early clinical development. Although statin... |
|
|
Legumain expression, activity and secretion are increased during monocyte-to-macrophage differentiation and inhibited by atorvastatin.
Biol. Chem. 396(1) , 71-80, (2014) Macrophages express several lysosomal cysteine proteases such as cathepsins and legumain. In this study, we assessed the expression, activity and secretion of legumain in cellular models of monocytes/... |
| atorvastatin calcium trihydrate |
| 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt, (βR,δR)-, hydrate (2:1:3) |
| Torvast |
| Atorvastatin Calcium Salt Trihydrate |
| Atorvastatin hemicalcium salt sesquihydrate |
| Lipitor |
| 1H-Pyrrole-1-heptanoicacid, 2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-,calcium salt, hydrate (2:1:3), (bR,dR)- |
| Calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate hydrate (1:2:3) |
| Sortis |
| Totalip |
查看所有供应商和价格请点击：