NBD-557

• 常用名: NBD-557
• 英文名: NBD-557
• CAS号: 333352-59-3
• 分子量: 382.29500
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₂₄BrN₃O₂
• 熔点: N/A
• 闪点: N/A

NBD-557用途

NBD-557是HIV-1抑制剂。

NBD-557名称

• 中文名: NBD-557
• 英文名: N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide

NBD-557生物活性

• 描述: NBD-557是HIV-1抑制剂。
• 相关类别:
  信号通路 >> 抗感染 >> HIV
  研究领域 >> 感染
• 参考文献:

  [1]. Sch?n A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB 3rd, Sodroski J, Freire E. Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120. Biochemistry. 2006 Sep 12;45(36):10973-80.

  [2]. Singh IP, Chauthe SK. Small molecule HIV entry inhibitors: Part II. Attachment and fusion inhibitors: 2004-2010. Expert Opin Ther Pat. 2011 Mar;21(3):399-416.

  [3]. Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK. Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4. Virology. 2005 Sep 1;339

  [4]. Narumi, Tetsuo et al. CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist. Bioorganic & Medicinal Chemistry Letters (2010), 20(19), 5853-5858.

NBD-557物理化学性质

• 分子式: C₁₇H₂₄BrN₃O₂
• 分子量: 382.29500
• 精确质量: 381.10500
• PSA: 73.72000
• LogP: 4.18220
• 储存条件: -20°C

NBD-557英文别名

• nbd-557
• 0ly