盐酸匹美西林

• 常用名: 盐酸匹美西林
• 英文名: Pivmecillinam hydrochloride
• CAS号: 32887-03-9
• 分子量: 476.030
• 密度: 1.3g/cm3
• 沸点: 581ºC at 760mmHg
• 分子式: C₂₁H₃₄ClN₃O₅S
• 熔点: 172-173°
• 闪点: 305.2ºC

盐酸匹美西林用途

Pivmecillinam盐酸盐是Mecillinam的口服型前提化合物，广谱抗生素。

盐酸匹美西林名称

• 中文名: 盐酸匹美西林
• 英文名: pivmecillinam hydrochloride

盐酸匹美西林生物活性

• 描述: Pivmecillinam hydrochloride (FL-1039 hydrochloride) 是Mecillinam的口服型前提化合物,广谱抗生素。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Nicolle LE. Pivmecillinam in the treatment of urinary tract infections. J Antimicrob Chemother. 2000 Aug;46 Suppl A:35-39.

  [2]. Graninger W. Pivmecillinam--therapy of choice for lower urinary tract infection. Int J Antimicrob Agents. 2003 Oct;22 Suppl 2:73-8.

  [3]. Holme E, et al. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet. 1989 Aug 26;2(8661):469-73.

盐酸匹美西林物理化学性质

• 密度: 1.3g/cm3
• 沸点: 581ºC at 760mmHg
• 熔点: 172-173°
• 分子式: C₂₁H₃₄ClN₃O₅S
• 分子量: 476.030
• 闪点: 305.2ºC
• 精确质量: 475.190765
• PSA: 113.81000
• LogP: 3.08940
• 外观性状: 粉末
• 储存条件: -20℃

盐酸匹美西林毒性和生态

盐酸匹美西林英文别名

• 2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
• 2-Pyrrolidinecarboxamide,1-(2,2-dimethyl-1-oxopropyl)-N-methyl
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(1E)-(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S,5R,6R)-, hydrochloride (1:1)
• [(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R,6R)-6-[(E)-(1-azepanylmethylene)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride (1:1)
• Piv-DL-Pro-NHMe