罗美昔布

• 常用名: 罗美昔布
• 英文名: Lumiracoxib
• CAS号: 220991-20-8
• 分子量: 293.721
• 密度: 1.4±0.1 g/cm3
• 沸点: 395.7±42.0 °C at 760 mmHg
• 分子式: C₁₅H₁₃ClFNO₂
• 熔点: 139-141ºC
• 闪点: 193.1±27.9 °C

罗美昔布用途

Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.

罗美昔布名称

• 中文名: 罗美昔布
• 英文名: lumiracoxib
• 中文别名: 2-[(2-氯-6-氟苯基)氨基」-5-甲基苯乙酸 | 鲁米昔布

罗美昔布物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 395.7±42.0 °C at 760 mmHg
• 熔点: 139-141ºC
• 分子式: C₁₅H₁₃ClFNO₂
• 分子量: 293.721
• 闪点: 193.1±27.9 °C
• 精确质量: 293.061890
• PSA: 49.33000
• LogP: 3.90
• 外观性状: 淡黄色固体
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.628
• 储存条件: -20°C Freezer

罗美昔布英文别名

• 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid
• Prexige (Novartis)
• 2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid
• {2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid
• Prexige
• COX189
• 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid
• Joicela
• Benzeneacetic acid, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-
• (2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid
• Lumiracoxib
• [14C]-Lumiracoxib
• 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid
• Lumiracoxib [USAN:INN]