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220991-20-8

220991-20-8结构式

常用中文名：罗美昔布
常用英文名：Lumiracoxib
CAS号：220991-20-8
分子式：C₁₅H₁₃ClFNO₂
分子量：293.721
相关类别：生物化工抑制剂神经信号通路(Neuronal Signaling) COX 抑制剂
发布时间：2018-08-23 07:01:28
更新时间：2025-10-23 13:15:52
Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.

中文名	罗美昔布
英文名	lumiracoxib
中文别名	2-[(2-氯-6-氟苯基)氨基」-5-甲基苯乙酸鲁米昔布
英文别名	2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid Prexige (Novartis) 2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid {2-[(2-Chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid Prexige COX189 5-methyl-2-(2'-chloro-6'-fluoroanilino)phenylacetic acid Joicela Benzeneacetic acid, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl- (2-((2-chloro-6-fluorophenyl)-amino)-5-methylphenyl)-acetic acid Lumiracoxib [14C]-Lumiracoxib 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid Lumiracoxib [USAN:INN]