Recoflavone

• 常用名: Recoflavone
• 英文名: Recoflavone
• CAS号: 203191-10-0
• 分子量: 386.352
• 密度: 1.3±0.1 g/cm3
• 沸点: 617.7±55.0 °C at 760 mmHg
• 分子式: C₂₀H₁₈O₈
• 熔点: N/A
• 闪点: 221.2±25.0 °C

Recoflavone用途

雷可黄酮是尤帕林的合成衍生物,对胃粘膜有保护作用。雷公藤黄酮具有治疗消化性溃疡病的潜力。

Recoflavone名称

• 英文名: 2-[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxochromen-7-yl]oxyacetic acid

Recoflavone生物活性

• 描述: 雷可黄酮是尤帕林的合成衍生物,对胃粘膜有保护作用。雷公藤黄酮具有治疗消化性溃疡病的潜力。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Choi SM, Seo MJ, Lee YG, et al. Effects of DA-6034, a flavonoid derivative, on mucin-like glycoprotein and ocular surface integrity in a rabbit model. Arzneimittelforschung. 2009;59(10):498-503.

  [2]. Kwak DS, Lee OY, Lee KN, et al. The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model. Gut Liver. 2016;10(3):406-411.

  [3]. Kim YW, Lee WH, Choi SM, et al. DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway. J Gastroenterol Hepatol. 2012;27(2):397-405.

  [4]. Nam SY, Kim JS, Kim JM, et al. DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis. Exp Biol Med (Maywood). 2008;233(2):180-191.

Recoflavone物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 617.7±55.0 °C at 760 mmHg
• 分子式: C₂₀H₁₈O₈
• 分子量: 386.352
• 闪点: 221.2±25.0 °C
• 精确质量: 386.100159
• PSA: 104.43000
• LogP: 2.56
• InChIKey: BCPQOBQIVJZOFL-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(OC)cc(OCC(=O)O)cc3o2)cc1OC
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.593

Recoflavone英文别名

• UNII-U96J5LG435
• Recoflavone
• {[2-(3,4-Dimethoxyphenyl)-5-methoxy-4-oxo-4H-chromen-7-yl]oxy}acetic acid
• 7-Carboxymethoxyloxy-3',4',5-trimethoxyflavone
• DA-6034
• Acetic acid, 2-[[2-(3,4-dimethoxyphenyl)-5-methoxy-4-oxo-4H-1-benzopyran-7-yl]oxy]-