HEXAHYDRO-1H-AZEPINYLCARBONYL-LEU-D-1-ME-TRP-DPAL

• 常用名: HEXAHYDRO-1H-AZEPINYLCARBONYL-LEU-D-1-ME-TRP-DPAL
• 英文名: FR 139317
• CAS号: 142375-60-8
• 分子量: 604.74000
• 密度: 1.27 g/cm3
• 沸点: 943.9ºC at 760 mmHg
• 分子式: C₃₃H₄₄N₆O₅
• 熔点: N/A
• 闪点: 524.6ºC

用途

FR 139317 is a highly potent and selective antagonist of ETA endothelin receptor, with Ki values of 1 nM and 7.3 μM for ETA and ETB subtypes, respectively.

名称

• 中文名: HEXAHYDRO-1H-AZEPINYLCARBONYL-LEU-D-1-ME-TRP-DPAL
• 英文名: (R)2-[(R)-2[(S)-2[[1-(hexahydro-1H-azepinyl)] carbonyl] amino-4-methylpentanoyl] amino-3-[3-(1-methyl-1H-indolyl)] propionyl] amino-3-(2-pyridyl) propionic acid

物理化学性质

• 密度: 1.27 g/cm3
• 沸点: 943.9ºC at 760 mmHg
• 分子式: C₃₃H₄₄N₆O₅
• 分子量: 604.74000
• 闪点: 524.6ºC
• 精确质量: 604.33700
• PSA: 145.66000
• LogP: 4.52360
• InChIKey: LIOKMIQQPDDTNO-UPRLRBBYSA-N
• SMILES: CC(C)CC(NC(=O)N1CCCCCC1)C(=O)NC(Cc1cn(C)c2ccccc12)C(=O)NC(Cc1ccccn1)C(=O)O
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.63
• 储存条件: 2-8°C，密闭，干燥

英文别名

• 4-BMA
• 1-Bma Or 4-Bma
• Side chain for iMipe
• 1-BMA
• B-METHYLAZETIDIN-2-ONE
• SS-METHYLAZETIDIN-2-ONE