盐酸左旋多巴甲酯

更新时间：2025-08-22 18:07:25

盐酸左旋多巴甲酯结构式	常用名	盐酸左旋多巴甲酯	英文名	L-3,4-Dihydroxyphenylalanine Methyl ester hydrochloride
	CAS号	1421-65-4	分子量	247.676
	密度	1.322g/cm3	沸点	384.4ºC at 760mmHg
	分子式	C₁₀H₁₄ClNO₄	熔点	N/A
	MSDS	美版	闪点	186.3ºC

盐酸左旋多巴甲酯用途

Melevodopa hydrochloride is a biochemical.

中文名	L-3,4-二羟基苯基丙氨酸甲酯盐酸
英文名	L-DOPA Methyl Ester Hydrochloride
中文别名	盐酸左旋多巴甲酯
英文别名	更多

密度	1.322g/cm3
沸点	384.4ºC at 760mmHg
分子式	C₁₀H₁₄ClNO₄
分子量	247.676
闪点	186.3ºC
精确质量	247.061142
PSA	92.78000
LogP	1.64290
外观性状	白色固体
蒸汽压	1.86E-06mmHg at 25°C
储存条件	-20°C
计算化学	1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:4 3.氢键受体数量:5 4.可旋转化学键数量:4 5.互变异构体数量:18 6.拓扑分子极性表面积92.8 7.重原子数量:16 8.表面电荷:0 9.复杂度:222 10.同位素原子数量:0 11.确定原子立构中心数量:1 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:2

危害码 (欧洲)	Xi
危险品运输编码	NONH for all modes of transport
海关编码	2923900090

甲醇

67-56-1

左旋多巴

59-92-7

~99%

盐酸左旋多巴甲酯

1421-65-4

文献：Journal of Medicinal Chemistry, , vol. 44, # 21 p. 3488 - 3503

左旋多巴

59-92-7

盐酸左旋多巴甲酯

1421-65-4

文献：US5952328 A1, ; US 5952328 A

乙醚

60-29-7

左旋多巴

59-92-7

盐酸左旋多巴甲酯

1421-65-4

文献：US5387610 A1, ;

盐酸左旋多巴甲酯上游产品 3
CAS号67-56-1 甲醇 CAS号59-92-7 左旋多巴 CAS号60-29-7 乙醚
盐酸左旋多巴甲酯下游产品 0

海关编码	2923900090
中文概述	2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Striatal astrocytes act as a reservoir for L-DOPA.

PLoS ONE 9(9) , e106362, (2014)

L-DOPA is therapeutically efficacious in patients with Parkinson's disease (PD), although dopamine (DA) neurons are severely degenerated. Since cortical astrocytes express neutral amino acid transport...

L-DOPA-induced dyskinesia in a rat model of Parkinson's disease is associated with the fluctuational release of norepinephrine in the sensorimotor striatum.

J. Neurosci. Res. 92(12) , 1733-45, (2014)

L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia (LID) is the most common complication of standard L-DOPA therapy for Parkinson's disease experienced by most parkinsonian patients. LID is asso...

Genome-wide microarray analysis identifies a potential role for striatal retrograde endocannabinoid signaling in the pathogenesis of experimental L-DOPA-induced dyskinesia.

Synapse 68(8) , 332-43, (2014)

l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most widely used drug for the treatment of Parkinson's disease. Unfortunately, chronic administration of this dopamine precursor causes L-DOPA-induced dysk...

L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride

MFCD00038958

L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride

methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate,hydrochloride

Methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1)

(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

Methyl L-DOPA hydrochloride

methyldopa hydrochloride