N'-(4-(二乙基氨基)-2-羟基亚苄基)异烟酰肼

• 常用名: N'-(4-(二乙基氨基)-2-羟基亚苄基)异烟酰肼
• 英文名: RSVA 405
• CAS号: 140405-36-3
• 分子量: 312.36600
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₂₀N₄O₂
• 熔点: N/A
• 闪点: N/A

用途

RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 also can be used for the research of obesity.

名称

• 中文名: N'-(4-(二乙基氨基)-2-羟基亚苄基)异烟酰肼
• 英文名: N'-[1-(4-diethylamino-2-hydroxyphenyl)methylidene]isonicotinohydrazide

物理化学性质

• 分子式: C₁₇H₂₀N₄O₂
• 分子量: 312.36600
• 精确质量: 312.15900
• PSA: 77.82000
• LogP: 2.78820
• 储存条件: 2-8°C， 干燥

英文别名

• p-(N,N-diethylamino)salicylaldehyde isonicotinoylhydrazone
• N'-[4-(diethylamino)-2-hydroxybenzylidene]isonicotinohydrazide
• Hit2Lead 5113025
• ST 91