纽莫康定 B0

更新时间：2024-01-02 08:14:14

纽莫康定 B0结构式	常用名	纽莫康定 B0	英文名	Pneumocandin B0
	CAS号	135575-42-7	分子量	1065.214
	密度	1.4±0.1 g/cm3	沸点	1442.9±65.0 °C at 760 mmHg
	分子式	C₅₀H₈₀N₈O₁₇	熔点	N/A
	MSDS	N/A	闪点	826.5±34.3 °C

纽莫康定 B0用途

Pneumocandin B0(L-688786)是Cancidas的合成中间体。

中文名	纽莫康定 B0
英文名	Pneumocandin B0
中文别名	纽莫康定 \| 纽莫康定B0(肺囊康定) \| 纽莫康定B0((肺囊康定)
英文别名	更多

描述	Pneumocandin B0(L-688786)是Cancidas的合成中间体。
相关类别	信号通路 >> 抗感染 >> 真菌研究领域 >> 感染
参考文献	[1]. Welch CJ, et al. Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0. J Chromatogr A. 2006 Jan 6;1101(1-2):204-13. [2]. Leonard WR Jr, et al. Synthesis of the antifungal beta-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0. J Org Chem. 2007 Mar 30;72(7):2335-43.

描述

Pneumocandin B0(L-688786)是Cancidas的合成中间体。

相关类别

信号通路 >> 抗感染 >> 真菌

研究领域 >> 感染

参考文献

[1]. Welch CJ, et al. Preparation and evaluation of novel stationary phases for improved chromatographic purification of pneumocandin B0. J Chromatogr A. 2006 Jan 6;1101(1-2):204-13.

[2]. Leonard WR Jr, et al. Synthesis of the antifungal beta-1,3-glucan synthase inhibitor CANCIDAS (caspofungin acetate) from pneumocandin B0. J Org Chem. 2007 Mar 30;72(7):2335-43.

密度	1.4±0.1 g/cm3
沸点	1442.9±65.0 °C at 760 mmHg
分子式	C₅₀H₈₀N₈O₁₇
分子量	1065.214
闪点	826.5±34.3 °C
精确质量	1064.564087
PSA	411.28000
LogP	-5.00
蒸汽压	0.0±0.3 mmHg at 25°C
折射率	1.630
储存条件	-20°C

N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1R)-3-Amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide

1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine-20-propanamide, 23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-9-[(10,12-dimethyl-1-oxotetradecyl)amino]tetracosahydro-β,2,11,12,15-pentahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxo-, (βR,2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-

PneumocandinB0

1H-Dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacycloheneicosine-20-propanamide, 23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-9-[(10,12-dimethyl-1-oxotetradecyl)amino]tetracosahydro-β,2,11 ,12,15-pentahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxo-, (βR,2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-

B0 PneuMocandin B0

pneumocandin Bo

Pneumocardin B0