甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物结构式
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常用名 | 甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物 | 英文名 | H-Gly-Pro-Arg-Pro-NH2 acetate salt |
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| CAS号 | 126047-75-4 | 分子量 | 424.49800 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H32N8O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
甘氨酸-脯氨酸-精氨酸-脯氨酸-氨基化合物用途H-Gly-Pro-Arg-Pro-NH2 是一种模拟纤维蛋白链中 N 末端 Gly-Pro-Arg 区域的肽。H-Gly-Pro-Arg-Pro-NH2 防止纤维蛋白聚合。 |
| 中文名 | H-GLY-PRO-ARG-PRO-NH2 |
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| 英文名 | (2S)-1-(2-aminoacetyl)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide |
| 英文别名 | 更多 |
| 描述 | H-Gly-Pro-Arg-Pro-NH2 是一种模拟纤维蛋白链中 N 末端 Gly-Pro-Arg 区域的肽。H-Gly-Pro-Arg-Pro-NH2 防止纤维蛋白聚合。 |
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| 相关类别 | |
| 参考文献 |
| 分子式 | C18H32N8O4 |
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| 分子量 | 424.49800 |
| 精确质量 | 424.25500 |
| PSA | 200.73000 |
| LogP | 0.01870 |
| InChIKey | SCCTZYGEMPQRCV-AVGNSLFASA-N |
| SMILES | NCC(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(N)=O |
| 外观性状 | 固体 |
| 储存条件 | 20°C |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 危险品运输编码 | NONH for all modes of transport |
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The synthetic peptide Gly-Pro-Arg-Pro-amide limits the plasmic digestion of fibrinogen in the same fashion as calcium ion.
Protein Sci. 1(12) , 1719-20, (1992)
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The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model.
J. Thromb. Haemost. 1(3) , 587-94, (2003) Although hirudin is better than heparin at preventing recurrent ischemia in patients with unstable angina, hirudin produces more bleeding. The purpose of this study was to use a rabbit arterial thromb... |
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Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin.
.PubMed ID Members of the Src family of kinases are abundant in platelets. Although their localization is known, their role(s) in platelet function are not well understood. Lyn is a Src-family kinase that partic... |
| Gly-Pro-Arg-Pro amide |
| L-Prolinamide,glycyl-L-prolyl-L-arginyl |