Bayer-18

• 常用名: Bayer-18
• 英文名: Bayer-18
• CAS号: 1251752-12-1
• 分子量: 390.455
• 密度: 1.3±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₉H₂₇FN₆O₂
• 熔点: N/A
• 闪点: N/A

Bayer-18用途

Bayer-18 is a selective TYK2 inhibitor, with an IC50 of 18.7nM on TYK2 as measured by TYK2 HTRF assays.

Bayer-18名称

• 英文名: 1-[3-({5-Fluoro-4-[(1-hydroxy-2-methyl-2-propanyl)amino]-2-pyrimidinyl}amino)phenyl]-3-(2-methyl-2-propanyl)urea

Bayer-18物理化学性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₁₉H₂₇FN₆O₂
• 分子量: 390.455
• 精确质量: 390.217957
• LogP: 1.85
• InChIKey: DYNMZYFOSRSMAC-UHFFFAOYSA-N
• SMILES: CC(C)(C)NC(=O)Nc1cccc(Nc2ncc(F)c(NC(C)(C)CO)n2)c1
• 折射率: 1.632

Bayer-18英文别名

• Urea, N-(1,1-dimethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethylethyl)amino]-2-pyrimidinyl]amino]phenyl]-
• 1-[3-({5-Fluoro-4-[(1-hydroxy-2-methyl-2-propanyl)amino]-2-pyrimidinyl}amino)phenyl]-3-(2-methyl-2-propanyl)urea