Bayer-18

Modify Date: 2024-09-10 10:37:42

Bayer-18 Structure
Bayer-18 structure
Common Name Bayer-18
CAS Number 1251752-12-1 Molecular Weight 390.455
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C19H27FN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bayer-18


Bayer-18 is a selective TYK2 inhibitor, with an IC50 of 18.7nM on TYK2 as measured by TYK2 HTRF assays.

 Names

Name 1-[3-({5-Fluoro-4-[(1-hydroxy-2-methyl-2-propanyl)amino]-2-pyrimidinyl}amino)phenyl]-3-(2-methyl-2-propanyl)urea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C19H27FN6O2
Molecular Weight 390.455
Exact Mass 390.217957
LogP 1.85
Index of Refraction 1.632

 Synonyms

Urea, N-(1,1-dimethylethyl)-N'-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethylethyl)amino]-2-pyrimidinyl]amino]phenyl]-
1-[3-({5-Fluoro-4-[(1-hydroxy-2-methyl-2-propanyl)amino]-2-pyrimidinyl}amino)phenyl]-3-(2-methyl-2-propanyl)urea
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