1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯

• 常用名: 1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯
• 英文名: Impurity F of Calcipotriol
• CAS号: 112875-61-3
• 分子量: 641.12600
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₉H₆₈O₃Si₂
• 熔点: N/A
• 闪点: N/A

用途

Impurity F of Calcipotriol是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。

1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯名称

• 中文名: 卡泊三醇的杂质F.
• 英文名: (E,1S,4R)-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-2-methylidenecyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-1-cyclopropylpent-2-en-1-ol

1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯生物活性

• 描述: Impurity F of Calcipotriol是钙泊三醇的杂质,钙泊三醇是1,25-Dihydroxyvitamin D3类似物。
• 相关类别:
  信号通路 >> 维生素 D 相关 >> VD/VDR
  研究领域 >> 癌症
• 参考文献:

  [1]. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240.

  [2]. Knutson et al (1997) Pharmacokinetics and systemic effect on calcium homeostasis of 1a,24-dihydroxyvitamin D2 in rats. Biochem.Pharmacol. 53 829.

  [3]. Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs 18 447.111

  [4]. Lise Binderup,, Erik Bramm. Effects of a novel vitamin D analogue MC 903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochemical Pharmacology. Volume 37, Issue 5, 1 March 1988, Pages 889-895

1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯物理化学性质

• 分子式: C₃₉H₆₈O₃Si₂
• 分子量: 641.12600
• 精确质量: 640.47100
• PSA: 38.69000
• LogP: 11.14960
• 储存条件: 2-8℃

1,3-双-O-(叔丁基二甲基甲硅烷基)骨化三烯英文别名

• 1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriene
• (1S,3R)-bis(tert-butyldimethylsilyloxy)-20(R)-(3'(S)-cyclopropyl-3'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(Z),7(E),10(19)-triene
• 1(S),3(R)-bis(tert-butyl-dimethylsilyloxy)-20(R)-(3'-cyclopropyl-3(S)'-hydroxyprop-1'(E)-enyl)-9,10-secopregna-5(Z),7(E),10(19)-triene
• UNII-4SP93VP62P
• Impurity F of Calcipotriol