16205-44-0

16205-44-0结构式

常用中文名：吡唑并[1,5-A]吡啶-3-甲酸乙酯
常用英文名：Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate
CAS号：16205-44-0
分子式：C₁₀H₁₀N₂O₂
分子量：190.19900
发布时间：2018-12-01 15:50:23
更新时间：2024-01-04 15:44:55

中文名	吡唑并[1,5-A]吡啶-3-甲酸乙酯
英文名	Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate
中文别名	吡唑并[1,5-a]吡啶-3-甲酸乙酯吡唑并[1,5-α]吡啶-3-甲酸乙酯
英文别名	MFCD06411542 ETHYL PYRAZOLO[1,5-A]PYRIDINE-3-CARBOXYLATE

密度	1.22g/cm3
沸点	134-135ºC/3mm
分子式	C₁₀H₁₀N₂O₂
分子量	190.19900
精确质量	190.07400
PSA	43.60000
LogP	1.51100
折射率	1.594
储存条件	常温密闭避光，通风干燥
稳定性	常温常压下稳定避免的物料：氧化物
分子结构	1、摩尔折射率：52.59 2、摩尔体积（m³/mol）：154.9 3、等张比容（90.2K）：402.0 4、表面张力（dyne/cm）：45.3 5、极化率（10^-24cm³）：20.85
计算化学	1.疏水参数计算参考值（XlogP）:1.3 2.氢键供体数量:0 3.氢键受体数量:3 4.可旋转化学键数量:3 5.互变异构体数量:无 6.拓扑分子极性表面积43.6 7.重原子数量:14 8.表面电荷:0 9.复杂度:220 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1.性状：未确定 2.密度（g/mL,25/4℃）：未确定 3.相对蒸汽密度（g/mL,空气=1）：未确定 4.熔点（ºC）：未确定 5.沸点（ºC,常压）：未确定 6.沸点（ºC,5.2kPa）：134-135°C/3mm 7.折射率：未确定 8. 闪点（ºC）：134-135°C/2.3mm 9. 比旋光度（º）：未确定 10.自燃点或引燃温度（ºC）：未确定 11.蒸气压（kPa,25ºC）：未确定 12.饱和蒸气压（kPa,60ºC）：未确定 13.燃烧热（KJ/mol）：未确定 14.临界温度（ºC）：未确定 15.临界压力（KPa）：未确定 16.油水（辛醇/水）分配系数的对数值：未确定 17.爆炸上限（%,V/V）：未确定 18.爆炸下限（%,V/V）：未确定 19.溶解性：未确定

Name:	Ethyl pyrazolo[1 5-a]pyridine-3-carboxylate Material Safety Data Sheet
Synonym:	None know
CAS:	16205-44-0

Section 1 - Chemical Product MSDS Name:Ethyl pyrazolo[1 5-a]pyridine-3-carboxylate Material Safety Data Sheet
Synonym:None know

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
16205-44-0	Ethyl pyrazolo[1,5-a]pyridine-3-carbox	95+%	unlisted

Hazard Symbols: XN
Risk Phrases: 22 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways.

Section 7 - HANDLING and STORAGE
Handling:
Use with adequate ventilation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 16205-44-0: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Oil
Color: Yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H10N2O2
Molecular Weight: 190.2

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 16205-44-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl pyrazolo[1,5-a]pyridine-3-carboxylate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 16205-44-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 16205-44-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 16205-44-0 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

生态学数据:

通常对水体是稍微有害的，不要将未稀释或大量产品接触地下水，水道或污水系统，未经政府许可勿将材料排入周围环境。

危害码 (欧洲)	Xi:Irritant;
海关编码	2933990090

6295-87-0

623-47-2

~71%

16205-44-0

文献：Loeber; Huebner; Utz; Gmeiner Journal of Medicinal Chemistry, 2001 , vol. 44, # 17 p. 2691 - 2694

上游产品 2
6295-87-0 623-47-2
下游产品 10
307308-03-8 362661-83-4 221470-50-4 25627-89-8
274-56-6 73957-66-1 5910-12-3 117782-76-0
16205-46-2 1207557-48-9

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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