57543-56-3

• 常用中文名：1-(6-甲氧基-2H-色烯-3-基)-1-乙酮
• 常用英文名：1-(6-METHOXY-2H-CHROMENE-3-YL)ETHAN-1-ONE
• CAS号：57543-56-3
• 分子式：C₁₂H₁₂O₃
• 分子量：204.22200
• 发布时间：2018-12-24 18:27:28
• 更新时间：2025-08-20 18:49:38

名称

• 中文名: 1-(6-甲氧基-2H-色烯-3-基)-1-乙酮
• 英文名: 1-(6-methoxy-2H-chromen-3-yl)ethanone
• 英文别名: Ketone,6-methoxy-2H-1-benzopyran-3-yl methyl; 3-acetyl-6-methoxy-2H-chromen; 3-acetyl-6-methoxy-2H-chromene; 6-Methoxy-3-acetyl-2H-chromene; 2H-1-BENZOPYRAN,3-ACETYL-6-METHOXY

物化性质

• 分子式: C₁₂H₁₂O₃
• 分子量: 204.22200
• 精确质量: 204.07900
• PSA: 35.53000
• LogP: 2.06000
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DJ2120000 CHEMICAL NAME : 2H-1-Benzopyran, 3-acetyl-6-methoxy- CAS REGISTRY NUMBER : 57543-56-3 BEILSTEIN REFERENCE NO. : 1244918 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H12-O3 MOLECULAR WEIGHT : 204.24 WISWESSER LINE NOTATION : T66 BO CHJ DV1 HO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 11,81,1976

合成路线

672-13-9 78-94-4 ~88% 57543-56-3

文献：Shin, Soon Young; Jung, Hyeryoung; Ahn, Seunghyun; Hwang, Doseok; Yoon, Hyuk; Hyun, Jiye; Yong, Yeonjoong; Cho, Hi Jae; Koh, Dongsoo; Lee, Young Han; Lim, Yoongho Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 6 p. 1809 - 1820

673-22-3 78-94-4 ~70% 57543-56-3

文献：Zhou, Long-Hua; Wang, Na; Zhang, Wei; Xie, Zong-Bo; Yu, Xiao-Qi Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 91, p. 37 - 43

672-13-9 78-94-4 78-93-3 ~76% 57543-56-3

文献：Adir et Cie Patent: US4975455 A1, 1990 ;

672-13-9 141-97-9 ~% 57543-56-3

文献：La Pietra, Valeria; Marinelli, Luciana; Cosconati, Sandro; Di Leva, Francesco Saverio; Nuti, Elisa; Santamaria, Salvatore; Pugliesi, Isabella; Morelli, Matteo; Casalini, Francesca; Rossello, Armando; La Motta, Concettina; Taliani, Sabrina; Visse, Robert; Nagase, Hideaki; Da Settimo, Federico; Novellino, Ettore European Journal of Medicinal Chemistry, 2012 , vol. 47, # 1 p. 143 - 152

150-76-5 ~% 57543-56-3

文献：Foroumadi, Alireza; Emami, Saeed; Sorkhi, Maedeh; Nakhjiri, Maryam; Nazarian, Zohreh; Heydari, Samaneh; Ardestani, Sussan K.; Poorrajab, Fatemeh; Shafiee, Abbas Chemical Biology and Drug Design, 2010 , vol. 75, # 6 p. 590 - 596