Catalytical promiscuity of α-amylase: synthesis of 3-substituted 2H-chromene derivatives via biocatalytic domino oxa-Michael/aldol condensations

LH Zhou, N Wang, W Zhang, ZB Xie, XQ Yu

文献索引：Zhou, Long-Hua; Wang, Na; Zhang, Wei; Xie, Zong-Bo; Yu, Xiao-Qi Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 91, p. 37 - 43

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被引用次数: 11

摘要

Abstract An facile and green one-pot route has been developed for the synthesis of chromenes using salicylaldehyde and α, β-unsaturated ketones. α-Amylase from Bacillus subtilis shows excellent catalytic activity and exerts good adaptability to different substrates in the reaction. This promiscuous enzyme-catalyzed domino reaction not only extends the application of α-amylase from B. subtilis for new chemical transformations, but also ...

673-22-3

2-羟基-4-甲氧基苯甲醛

~70%

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