1006376-62-0

• 常用中文名：(1R,2R)-2-(3,4-二氟苯基)环丙烷甲酰胺
• 常用英文名：(1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxamide
• CAS号：1006376-62-0
• 分子式：C₁₀H₉F₂NO
• 分子量：197.181
• 发布时间：2018-12-29 23:23:47
• 更新时间：2025-08-25 13:07:20

名称

• 中文名: 替卡格雷中间体
• 英文名: (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide
• 英文别名: (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide; Cyclopropanecarboxamide, 2-(3,4-difluorophenyl)-, (1R,2R)-; (1R,2R)-2-(3,4-difluorophenyl)-1-cyclopropanecarboxamide

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 347.9±42.0 °C at 760 mmHg
• 分子式: C₁₀H₉F₂NO
• 分子量: 197.181
• 闪点: 164.2±27.9 °C
• 精确质量: 197.065216
• PSA: 44.08000
• LogP: 0.65
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.556

合成路线

1006376-61-9 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

376608-70-7 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

220352-36-3 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

1006376-60-8 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

1006376-63-1 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

367-11-3 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

51336-95-9 ~% 1006376-62-0

文献：Zhang, Hao; Liu, Jun; Zhang, Luyong; Kong, Lingyi; Yao, Hequan; Sun, Hongbin Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3598 - 3602

上下游产品

上游产品  7
1006376-61-9 376608-70-7 220352-36-3 1006376-60-8
1006376-63-1 367-11-3 51336-95-9
下游产品  1
274693-27-5