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57625-97-5

57625-97-5结构式

常用中文名：琥珀酸西苯唑啉
常用英文名：Cibenzoline succinate
CAS号：57625-97-5
分子式：C₄₀H₄₂N₄O₄
分子量：642.78600
发布时间：2018-09-17 16:51:10
更新时间：2024-01-14 07:24:25

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中文名	琥珀酸西苯唑啉
英文名	butanedioic acid,2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
英文别名	2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate (2:1) Succinic acid,compound with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2) EINECS 260-856-8 Butanedioic acid,compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2) 1H-Imidazole,4,5-dihydro-2-(2,2-diphenylcyclopropyl)-,succinate (2:1)

沸点	449.2ºC at 760 mmHg
分子式	C₄₀H₄₂N₄O₄
分子量	642.78600
闪点	225.5ºC
精确质量	642.32100
PSA	123.38000
LogP	5.45320

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI4804900

CAS REGISTRY NUMBER :: 57625-97-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C36-H36-N4.C4-H6-O4

MOLECULAR WEIGHT :: 642.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 300 mg/kg/22W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness

REFERENCE :: IEDIEP Internal Medicine. (The Japanese Society of Internal Medicine, 34-3, 3-chome, Hongo, Bunkyo-ku, Tokyo 113, Japan) V.31- 1992- Volume(issue)/page/year: 35,512,1996

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 41500 ug/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 22,4485,1988