788799-13-3

• 常用中文名：AFP-07 free acid
• 常用英文名：AFP-07 free acid
• CAS号：788799-13-3
• 分子式：C₂₂H₃₀F₂O₅
• 分子量：412.467
• 发布时间：2016-04-24 10:55:00
• 更新时间：2025-08-25 10:45:06
• AFP 07 free acid is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds.

名称

• 英文名: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid
• 英文别名: AFP-07 free acid; (5Z)-5-{(3aR,4R,5R,6aS)-3,3-Difluoro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-yn-1-yl]hexahydro-2H-cyclopenta[b]furan-2-ylidene}pentanoic acid; UNII-69PPR64XJA; (5Z)-5-{(3aR,4R,5R,6aS)-3,3-Difluoro-5-hydroxy-4-[(1E,3S,4S)-3-hydroxy-4-methyl-1-nonen-6-yn-1-yl]hexahydro-2H-cyclopenta[b]furan-2-ylidene}pentanoic acid (non-preferred name)

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 557.8±50.0 °C at 760 mmHg
• 分子式: C₂₂H₃₀F₂O₅
• 分子量: 412.467
• 闪点: 291.1±30.1 °C
• 精确质量: 412.206116
• PSA: 86.99000
• LogP: 1.93
• 蒸汽压: 0.0±3.4 mmHg at 25°C
• 折射率: 1.541