6795-60-4

• 常用中文名：诺乙烯酮
• 常用英文名：Deprodone
• CAS号：6795-60-4
• 分子式：C₂₀H₂₈O₂
• 分子量：300.43500
• 发布时间：2018-08-08 19:19:54
• 更新时间：2024-01-21 17:56:27

名称

• 中文名: 诺乙烯酮
• 英文名: (8R,9S,10R,13S,14S,17R)-17-ethenyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
• 英文别名: Nor-progestelea; 17-Vinyl-19-nortestosterone; Norvinisterone; Norvinisterona [INN-Spanish]; SC 4641; Norvinisteronum [INN-Latin]; Neoprogestin

物化性质

• 密度: 1.11g/cm3
• 沸点: 444ºC at 760 mmHg
• 分子式: C₂₀H₂₈O₂
• 分子量: 300.43500
• 闪点: 189.2ºC
• 精确质量: 300.20900
• PSA: 37.30000
• LogP: 4.04530
• 折射率: 1.565

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RC8899550 CHEMICAL NAME : 19-Nor-17-alpha-pregna-4,20-dien-3-one, 17-hydroxy- CAS REGISTRY NUMBER : 6795-60-4 LAST UPDATED : 199606 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H28-O2 MOLECULAR WEIGHT : 300.48 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 28 mg/kg SEX/DURATION : male 14 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 112 mg/kg SEX/DURATION : male 14 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 71,500,1958 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral DOSE : 8 mg/kg SEX/DURATION : male 3 week(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct REFERENCE : 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,29,1965 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 500 ug/kg SEX/DURATION : female 5 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 142,469,1962