2127-01-7

• 常用中文名：氯索隆
• 常用英文名：clorexolone
• CAS号：2127-01-7
• 分子式：C₁₄H₁₇ClN₂O₃S
• 分子量：328.81400
• 发布时间：2018-03-13 08:00:00
• 更新时间：2025-08-23 17:20:06

名称

• 中文名: 氯索隆
• 英文名: 6-chloro-2-cyclohexyl-3-oxo-1H-isoindole-5-sulfonamide
• 英文别名: Clorexolonum [INN-Latin]; 6-chloro-2-cyclohexyl-3-oxo-1,3-dihydro-isoindole-5-sulfonic acid amide; Flonatril; Clorexolona [INN-Spanish]; clorexolone; Klorex; Chlorexolone; Cloresolone [DCIT]; Nefrolan; Clorexolon

物化性质

• 密度: 1.447g/cm3
• 沸点: 577.2ºC at 760mmHg
• 分子式: C₁₄H₁₇ClN₂O₃S
• 分子量: 328.81400
• 闪点: 302.9ºC
• 精确质量: 328.06500
• PSA: 88.85000
• LogP: 3.99490
• 蒸汽压: 2.54E-13mmHg at 25°C
• 折射率: 1.631

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NR3538000 CHEMICAL NAME : 5-Isoindolinesulfonamide, 6-chloro-2-cyclohexyl-3-oxo- CAS REGISTRY NUMBER : 2127-01-7 BEILSTEIN REFERENCE NO. : 0493411 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C14-H17-Cl-N2-O3-S MOLECULAR WEIGHT : 328.84 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 21,775,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 120 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,65,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,257,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation Kidney, Ureter, Bladder - urine volume increased REFERENCE : BFPHA8 Bulletin of the Faculty of Pharmacy (Cairo University). (Faculty of Pharmacy, Cairo Univ., Cairo, Egypt) V.1- 1961/62- Volume(issue)/page/year: 10,155,1971 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 230 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,65,1966

安全

• 海关编码: 2935009090

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%