CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
DJ7390000
-
CHEMICAL NAME :
-
Benzo(a)pyrene, 6-methyl-
-
CAS REGISTRY NUMBER :
-
2381-39-7
-
BEILSTEIN REFERENCE NO. :
-
2213526
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
14
-
MOLECULAR FORMULA :
-
C21-H14
-
MOLECULAR WEIGHT :
-
266.35
-
WISWESSER LINE NOTATION :
-
L D6 B6666 2AB TJ J1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
479 ug/kg/60D-I
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Administration onto the skin
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
43 mg/kg/20W-I
-
TOXIC EFFECTS :
-
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
40 mg/kg
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Unreported
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
80 mg/kg/8D-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Administration onto the skin
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
4260 ug/kg
-
TOXIC EFFECTS :
-
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
80 mg/kg
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Administration onto the skin
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
32 mg/kg/20W-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Administration onto the skin
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
32 mg/kg/20W-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
-
TYPE OF TEST :
-
TD - Toxic dose (other than lowest)
-
ROUTE OF EXPOSURE :
-
Administration onto the skin
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
170 mg/kg/20W-I
-
TOXIC EFFECTS :
-
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
-
TYPE OF TEST :
-
DNA adduct
MUTATION DATA
-
TYPE OF TEST :
-
DNA adduct
-
TEST SYSTEM :
-
Mammal - species unspecified Lymphocyte
-
DOSE/DURATION :
-
30 umol/L
-
REFERENCE :
-
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 47,87,1983
|
