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58-20-8生产厂家

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58-20-8

58-20-8结构式
58-20-8结构式

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中文名 环戊丙酸睾酮
英文名 testosterone cypionate
中文别名 1-睾酮环戊丙酸酯
USP限制 环戊丙酸睾酮
英文别名 Jectatest
Depo
Malogen CYP
Testosterone cyclopentylpropionate
Durandro
MFCD00053944
Testodrin prolongatum
Andro-Cyp
(8R,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl-3-cyclopentylpropanoat
Pertestis
VIRILON
Testosterone 17b-Cypionate
Testosterone 17β-cyclopentanepropionate
depAndro 200
depAndro 100
Testosterone cypionate
DEPOVIRIN
Testosterone, cyclopentanepropionate
Testosterone 17b-Cyclopentanepropionate
depo-testosterone
3-cyclopentylpropanoate de (8R,9S,10R,13S,14S,17S)-10,13-diméthyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-1H-cyclopenta[a]phénanthrén-17-yle
EINECS 200-368-4
Testosterone 17β-cypionate
(17β)-3-Oxoandrost-4-en-17-yl 3-cyclopentylpropanoate
Cyclopentanepropanoic acid, (17β)-3-oxoandrost-4-en-17-yl ester
Depotest
17b-(3-Cyclopentyl-1-oxopropoxy)androst-4-en-3-one
Testergon
Testex Leo
Depo-testosterone cyclopentylpropionate
Dep-Test
T-Ionate-P.A
Androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17β)-
(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl 3-cyclopentylpropanoate
Androst-4-en-3-one, 17- (3-cyclopentyl-1-oxopropoxy)-, (17β)-
Testosteronecypionate
密度 1.1±0.1 g/cm3
沸点 525.9±50.0 °C at 760 mmHg
熔点 98 - 104ºC
分子式 C27H40O3
分子量 412.605
闪点 223.9±30.2 °C
精确质量 412.297760
PSA 43.37000
LogP 6.93
外观性状 白色至灰白色结晶粉末
蒸汽压 0.0±1.4 mmHg at 25°C
折射率 1.546
储存条件 2-8°C
分子结构

1、 摩尔折射率:118.41

2、 摩尔体积(cm3/mol):373.8

3、 等张比容(90.2K):961.2

4、 表面张力(dyne/cm):43.7

5、 极化率(10-24cm3):46.94


Section 1. Chemical Product and Company Identification
Testosterone cypionate
Common Name/
Trade Name
Testosterone cypionate

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention if irritation occurs.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsCLOSED CUP: Higher than 93.3°C (200°F).
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various SubstancesNon-flammable in presence of shocks.
Explosion Hazards in Presence Slightly explosive in presence of open flames and sparks.
Non-explosive in presence of shocks.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
As with most organic solids, fire is possible at elevated temperatures. When heated to decomposition it emits
Special Remarks on
acrid smoke and irritating fumes.
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
Hazardsexplosion hazard.

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
Testosterone cypionate

Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
breathe dust. Wear suitable protective clothing. If you feel unwell, seek medical attention and show the label
when possible. Keep away from incompatibles such as oxidizing agents.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
light-resistant containers.

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Crystalline powder)OdorSlight.
TasteNot available.
Molecular Weight412.61 g/mole
ColorWhite. Off-white.
pH (1% soln/water)Not applicable.
Not available.
Boiling Point
Melting Point98°C (208.4°F) - 104 C.
Not available.
Critical Temperature
Specific GravityNot available.
Vapor PressureNot applicable.
Vapor DensityNot available.
VolatilityNot available.
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesNot available.
SolubilityEasily soluble in diethyl ether.
Insoluble in cold water, hot water.
Freely soluble in chloroform, dioxane, alcohol.

Section 10. Stability and Reactivity Data
StabilityThe product is stable.
Instability TemperatureNot available.
Conditions of InstabilityExcess heat and incompatible materials
Incompatibility with various Reactive with oxidizing agents.
substances
Testosterone cypionate
Non-corrosive in presence of glass.
Corrosivity
Special Remarks onSensitive to light.
Reactivity
Special Remarks onNot available.
Corrosivity
Will not occur.
Polymerization

Section 11. Toxicological Information
Routes of EntryAbsorbed through skin. Inhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on HumansTERATOGENIC EFFECTS: Classified POSSIBLE for human.
DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Reproductive system/toxin/male
[POSSIBLE].
May cause damage to the following organs: blood, the reproductive system, liver.
Other Toxic Effects onSlightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.
Humans
Special Remarks onLD50 [Mouse] - Route: Intraperitoneal; Dose: >1000 mg/ kg
Toxicity to Animals
Special Remarks onMay cause adverse reproductive effects and birth defects.
Chronic Effects on HumansMay affect genetic material.
May cause cancer
Special Remarks on otherPotential Effects of Overexposure:
Toxic Effects on HumansAnabolic steroid
Skin: May cause skin irritation. May be absorbed through skin
Eyes: Dust may cause eye irritation.
Inhalation: Dust may cause respiratory tract irritaiton.
Ingestion: May cause gastrointestinal tract irritation with upset stomach or stomach pain, nausea, vomiting,
diarrhea. May cause water and salt retention (edema), weight gain, acne and muscular development. Other
symptoms may include headache, unusual tiredness, dizziness, trouble sleeping, increased pubic hair growth,
change in sex drive. Females may also experience virilizing side effects such as facial hair, deepening of the
voice, and menstrual irregularities. Effects of chronic overexposure in women include male-pattern baldness,
excessive body hair, prominant musculature, and hypertrophy of the clitoris, decreased breast size, oily skin,
impaired fertility. Effects generally slowly subside on discontinuation of exposure, but with prolonged
overexposure in women some effects may become irreversible. Overexposure in males may lead to feminizing
side effects (breast enlargement and or soreness), and decreased spermatogenesis or impaired fertility due to
inhibition of gonadotropin secretion and metabolic conversion of androgens to estrogens. Other symptoms of
overexposure in males may include frequent or continuing erections, chills, pain in the scrotum or groin, difficulty
urinating, decreased testicle size, and aggressive behavior.
May also affect blood(clotting disorders, elevated cholesterol levels, change in red blood cell count), and liver.
Effects on the liver may cause yellowing of the skin or eyes (jaundice).
Chronic exposure may cause hypersensitization, masculinization in females, heart problems in males, impaired
fertility in males and females and cancer.
Medical Conditions Aggravated by Exposure: Hypersensitivity to material, males with breast or prostate cancer,
hypercalcemia resulting from osteolysis, pre-exisiting liver, kidney, or heart problems, and enlarged prostate gland.

Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the ProductsThe product itself and its products of degradation are not toxic.
of Biodegradation
Testosterone cypionate
Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental
Waste Disposal
control regulations.

Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
Not applicable.
Identification
Special Provisions forNot applicable.
Transport
DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
Federal and StateCalifornia prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:
Regulations
Testosterone cypionate
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause reproductive harm (female) which would require a warning under the statute: Testosterone cypionate
(Listed as Anabolic Steroid)
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause reproductive harm (male) which would require a warning under the statute: Testosterone cypionate (Listed
as Anabolic Steroid)
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: Testosterone cypionate
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer which would require a warning under the statute: Testosterone cypionate (List3ed as Testosterone
and its Esters)
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found
Proposition 65to cause cancer which would require a warning under the statute: Testosterone cypionate
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: Testosterone cypionate
Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC)R45- May cause cancer.S36/37- Wear suitable protective clothing and
R63- Possible risk of harm to thegloves.
unborn child.S46- If swallowed, seek medical advice
immediately and show this container or label.
S53- Avoid exposure - obtain special
instructions before use.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
Testosterone cypionate
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Testosterone cypionate
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is
combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper
methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products,


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XA3066000
CHEMICAL NAME :
Testosterone, cyclopentanepropionate
CAS REGISTRY NUMBER :
58-20-8
BEILSTEIN REFERENCE NO. :
3174363
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C27-H40-O3
MOLECULAR WEIGHT :
412.67

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,487,1982 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
4286 ug/kg
SEX/DURATION :
male 2 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 55,725,1952 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5357 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 166 (estimated) No. of Female Employees: 105 (estimated)

符号 GHS08
GHS08
信号词 Danger
危害声明 H350-H361
警示性声明 P201-P280-P308 + P313
危害码 (欧洲) T
风险声明 (欧洲) R45
安全声明 (欧洲) S53-S22-S26-S36
危险品运输编码 NONH for all modes of transport
WGK德国 3
RTECS号 XA3066000
海关编码 2937290018

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文献:Journal of the American Chemical Society, , vol. 75, p. 650,652, 6359

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文献:Journal of the American Chemical Society, , vol. 79, p. 4472,4474 US2566358 , ; DE896805 , ;

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文献:Journal of the American Chemical Society, , vol. 75, p. 650,652, 6359

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文献:Journal of the American Chemical Society, , vol. 75, p. 650,652, 6359
海关编码 2937290018