352458-37-8

• 常用中文名：德拉沙星葡甲胺
• 常用英文名：Delafloxacin meglumine
• CAS号：352458-37-8
• 分子式：C₂₅H₂₉ClF₃N₅O₉
• 分子量：635.974
• 相关类别： 信号通路 抗感染 细菌
• 发布时间：2018-05-05 08:00:00
• 更新时间：2025-08-25 19:23:19

名称

• 中文名: 德拉沙星葡甲胺
• 英文名: 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid,(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
• 英文别名: Delafloxacin meglumine; 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-7-(3-hydroxy-1-azetidinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1); D-Glucitol,1-deoxy-1-(methylamino)-,1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylate (salt); UNII-N7V53U4U4T; Delafloxacin meglumine (USAN); 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-, compd. with D-glucitol, 1-deoxy-1-(methylamino)- (1:1); 1-Deoxy-1-(methylamino)-D-glucitol 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate (salt); Delafloxacin (meglumine)

物化性质

• 分子式: C₂₅H₂₉ClF₃N₅O₉
• 分子量: 635.974
• 精确质量: 635.160583
• PSA: 235.59000
• 储存条件: 2-8℃

生物活性

• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染
• 参考文献:

  [1]. Gunderson SM, Hayes RA, Quinn JP, In vitro pharmacodynamic activities of ABT-492, a novel quinolone, compared to those of levofloxacin against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Antimicrob Agents Chemother. 2004 Jan;48(1):203-8.

  [2]. Goldstein EJ, Citron DM, Merriam CV, In vitro activities of ABT-492, a new fluoroquinolone, against 155 aerobic and 171 anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. Antimicrob Agents Chemother. 2003 Sep;47(9):3008-11.

  [3]. Nilius AM, Shen LL, Hensey-Rudloff D, In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone. Antimicrob Agents Chemother. 2003 Oct;47(10):3260-9.