219754-02-6

• 常用中文名：(1R,2S,5S)-3-(叔丁氧羰基)-6,6-二甲基-3-氮杂双环[3.1.0]己烷-2-羧酸
• 常用英文名：Boceprevir interMediate
• CAS号：219754-02-6
• 分子式：C₁₃H₂₁NO₄
• 分子量：255.31000
• 发布时间：2016-10-03 08:33:40
• 更新时间：2025-08-25 19:32:19

名称

• 中文名: (1R,2S,5S)-3-(叔丁氧羰基)-6,6-二甲基-3-氮杂双环[3.1.0]己烷-2-羧酸
• 英文名: (1R,2S,5S)-6,6-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
• 英文别名: aza016

物化性质

• 分子式: C₁₃H₂₁NO₄
• 分子量: 255.31000
• 精确质量: 255.14700
• PSA: 66.84000
• LogP: 1.90040
• 储存条件: 2-8°C， 避光干燥

合成路线

569679-06-7 ~84% 219754-02-6

文献：Nair, Latha G.; Saksena, Anil; Lovey, Raymond; Sannigrahi, Mousumi; Wong, Jesse; Kong, Jianshe; Fu, Xiaoyong; Girijavallabhan, Viyyoor Journal of Organic Chemistry, 2010 , vol. 75, # 4 p. 1285 - 1288

1026427-11-1 ~% 219754-02-6

文献：Zhang, Rui; Madalengoitia, Jose S. Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 330 - 331

219753-99-8 ~% 219754-02-6

文献：Zhang, Rui; Madalengoitia, Jose S. Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 330 - 331

134107-65-6 ~% 219754-02-6

文献：Venkatraman, Srikanth; Bogen, Stephane L.; Arasappan, Ashok; Bennett, Frank; Chen, Kevin; Jao, Edwin; Liu, Yi-Tsung; Lovey, Raymond; Hendrata, Siska; Huang, Yuhua; Pan, Weidong; Parekh, Tejal; Pinto, Patrick; Popov, Veljko; Pike, Russel; Ruan, Sumei; Santhanam, Bama; Vibulbhan, Bancha; Wu, Wanli; Yang, Weiying; Kong, Jianshe; Liang, Xiang; Wong, Jesse; Liu, Rong; Butkiewicz, Nancy; Chase, Robert; Hart, Andrea; Agrawal, Sony; Ingravallo, Paul; Pichardo, John; Kong, Rong; Baroudy, Bahige; Malcolm, Bruce; Guo, Zhuyan; Prongay, Andrew; Madison, Vincent; Broske, Lisa; Cui, Xiaoming; Cheng, Kuo-Chi; Hsieh, Yunsheng; Brisson, Jean-Marc; Prelusky, Danial; Korfmacher, Walter; White, Ronald; Bogdanowich-Knipp, Susan; Pavlovsky, Anastasia; Bradley, Prudence; Saksena, Anil K.; Ganguly, Ashit; Piwinski, John; Girijavallabhan, Viyyoor; Njoroge, F. George Journal of Medicinal Chemistry, 2006 , vol. 49, # 20 p. 6074 - 6086

103201-79-2 ~% 219754-02-6

文献：Venkatraman, Srikanth; Bogen, Stephane L.; Arasappan, Ashok; Bennett, Frank; Chen, Kevin; Jao, Edwin; Liu, Yi-Tsung; Lovey, Raymond; Hendrata, Siska; Huang, Yuhua; Pan, Weidong; Parekh, Tejal; Pinto, Patrick; Popov, Veljko; Pike, Russel; Ruan, Sumei; Santhanam, Bama; Vibulbhan, Bancha; Wu, Wanli; Yang, Weiying; Kong, Jianshe; Liang, Xiang; Wong, Jesse; Liu, Rong; Butkiewicz, Nancy; Chase, Robert; Hart, Andrea; Agrawal, Sony; Ingravallo, Paul; Pichardo, John; Kong, Rong; Baroudy, Bahige; Malcolm, Bruce; Guo, Zhuyan; Prongay, Andrew; Madison, Vincent; Broske, Lisa; Cui, Xiaoming; Cheng, Kuo-Chi; Hsieh, Yunsheng; Brisson, Jean-Marc; Prelusky, Danial; Korfmacher, Walter; White, Ronald; Bogdanowich-Knipp, Susan; Pavlovsky, Anastasia; Bradley, Prudence; Saksena, Anil K.; Ganguly, Ashit; Piwinski, John; Girijavallabhan, Viyyoor; Njoroge, F. George Journal of Medicinal Chemistry, 2006 , vol. 49, # 20 p. 6074 - 6086

219754-00-4 ~70% 219754-02-6

文献：Zhang, Rui; Madalengoitia, Jose S. Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 330 - 331

24424-99-5 ~% 219754-02-6

文献：Zhang, Rui; Madalengoitia, Jose S. Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 330 - 331