162204-20-8

• 常用中文名：5'-脱氧-5-氟-N-[(戊氧基)羰基]胞苷 2',3'-二乙酸酯
• 常用英文名：5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate
• CAS号：162204-20-8
• 分子式：C₁₉H₂₆FN₃O₈
• 分子量：443.423
• 发布时间：2018-08-03 08:57:01
• 更新时间：2024-01-02 23:23:52

名称

• 中文名: 5'-脱氧-5-氟-N-[(戊氧基)羰基]胞苷 2',3'-二乙酸酯
• 英文名: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate
• 英文别名: 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine; [(2R,3R,4R,5R)-4-acetyloxy-5-[5-fluoro-2-oxo-4-(pentoxycarbonylamino)pyrimidin-1-yl]-2-methyloxolan-3-yl] acetate; Cytidine, 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-, 2',3'-diacetate; T6NVNJ DMVO5 EF A- BT5OTJ COV1 DOV1 E1 &&Ribo-β-D Form; 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate; 5`-deoxy-5-fluore-N-[(pentoyloxy)carbonyl]cytidine 2`,3`-diacetate; Capecitabine Impurity 7

物化性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 111 °C
• 分子式: C₁₉H₂₆FN₃O₈
• 分子量: 443.423
• 精确质量: 443.170380
• PSA: 135.05000
• LogP: 2.14
• 外观性状: 固体;White to Almost white powder to crystal
• 折射率: 1.567
• 储存条件: 0-10°C;存放于惰性气体之中;避免空气,加热
• 水溶解性: 可溶于：甲醇

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

37076-71-4 862508-03-0 ~28% 162204-20-8

文献：Coll Farma S.L. Patent: EP2241556 A1, 2010 ; Location in patent: Page/Page column 9 ;

638-41-5 161599-46-8 ~% 162204-20-8

文献：Shimma, Nobuo; Umeda, Isao; Arasaki, Motohiro; Murasaki, Chikako; Masubuchi, Kazunao; Kohchi, Yasunori; Miwa, Masanori; Ura, Masako; Sawada, Noriaki; Tahara, Hitoshi; Kuruma, Isamu; Horii, Ikuo; Ishitsuka, Hideo Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 7 p. 1697 - 1706

1071455-34-9 27821-07-4 ~% 162204-20-8

文献：Organic Letters, , vol. 14, # 13 p. 3348 - 3351

638-41-5 41108-04-7 27821-07-4 ~% 162204-20-8

文献：Organic Letters, , vol. 14, # 13 p. 3348 - 3351

638-41-5 ~% 162204-20-8

文献：Organic Letters, , vol. 14, # 13 p. 3348 - 3351

27821-07-4 ~% 162204-20-8

文献：Bioorganic and Medicinal Chemistry, , vol. 8, # 7 p. 1697 - 1706

上下游产品

上游产品  6
37076-71-4 862508-03-0 638-41-5 161599-46-8
27821-07-4 41108-04-7
下游产品  1
154361-50-9

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%