13118-10-0

• 常用中文名：1-甲基-3-(alpha-环戊基扁桃酰氧基)吡咯烷盐酸盐
• 常用英文名：1-Methyl-3-(alpha-Cyclopentylmandeloyloxy)Pyrrolidinehydrochloride
• CAS号：13118-10-0
• 分子式：C₁₈H₂₆ClNO₃
• 分子量：339.85700
• 发布时间：2018-06-18 19:06:24
• 更新时间：2024-01-02 11:35:02

名称

• 中文名: 1-甲基-3-(alpha-环戊基扁桃酰氧基)吡咯烷盐酸盐
• 英文名: (1-methylpyrrolidin-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate,hydrochloride
• 中文别名: 1-甲基-3-(A-环戊基扁桃酰氧基)吡咯烷盐酸盐; 1-甲基-3-(Α-环戊基扁桃酰氧基)吡咯烷盐酸盐
• 英文别名: Mandelic acid,1-methyl-3-pyrrolidinyl ester,hydrochloride; AHR-376; 1-Methyl-3-(alpha-Cyclopentylmandeloyloxy)Pyrrolidinehydrochloride

物化性质

• 密度: 1.17g/cm3
• 沸点: 434.6ºC at 760mmHg
• 分子式: C₁₈H₂₆ClNO₃
• 分子量: 339.85700
• 闪点: 216.7ºC
• 精确质量: 339.16000
• PSA: 49.77000
• LogP: 3.05160
• 蒸汽压: 2.52E-08mmHg at 25°C
• 折射率: 1.577
• 储存条件: 库房通风低温干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OO7340000 CHEMICAL NAME : Mandelic acid, alpha-cyclopentyl-, 1-methyl-3-pyrrolidinyl ester, hydrochloride CAS REGISTRY NUMBER : 13118-10-0 LAST UPDATED : 198910 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C18-H25-N-O3.Cl-H MOLECULAR WEIGHT : 339.90 WISWESSER LINE NOTATION : T5NTJ A1 COVXQR&- AL5TJ &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 14 ug/kg/D TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - toxic psychosis REFERENCE : CPAJAK Canadian Psychiatric Association Journal. (Ottawa, Ont., Canada) V.1-23, 1956-78. For publisher information, see CJPSDF. Volume(issue)/page/year: 11,S141,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,523,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,523,1960