769965-95-9

• 常用中文名：5'-氟螺[环丙烷-1,3'-二氢吲哚]-2'-酮
• 常用英文名：5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one
• CAS号：769965-95-9
• 分子式：C₁₀H₈FNO
• 分子量：177.17500
• 发布时间：2016-03-17 20:47:08
• 更新时间：2025-08-25 11:58:34

名称

• 中文名: 5'-氟螺[环丙烷-1,3'-二氢吲哚]-2'-酮
• 英文名: 5-fluorospiro[1H-indole-3,1'-cyclopropane]-2-one
• 英文别名: 5-fluoro-siprocyclopropyloxindole; 5'-FLUOROSPIRO[CYCLOPROPANE-1,3'-INDOLIN]-2'-ONE

物化性质

• 密度: 1.386g/cm3
• 沸点: 351.775ºC at 760 mmHg
• 分子式: C₁₀H₈FNO
• 分子量: 177.17500
• 闪点: 166.548ºC
• 精确质量: 177.05900
• PSA: 29.10000
• LogP: 1.94740
• 折射率: 1.623
• 储存条件: 2-8℃，密封，干燥

安全

• 危害码 (欧洲): Xi

合成路线

769965-94-8 ~98% 769965-95-9

文献：IRM LLC Patent: WO2005/18568 A2, 2005 ; Location in patent: Page/Page column 36 ; WO 2005/018568 A2

56341-41-4 106-93-4 ~% 769965-95-9

文献：NOVARTIS AG; ATKINSON, Benjamin; BEATTIE, David; CULSHAW, Andrew James; DALE, James; DEVEREUX, Nicholas James; MCKENNA, Jeffrey Patent: WO2011/92293 A2, 2011 ; Location in patent: Page/Page column 85 ; WO 2011/092293 A1

769965-93-7 ~% 769965-95-9

文献：Tully, David C.; Liu, Hong; Chatterjee, Arnab K.; Alper, Phil B.; Williams, Jennifer A.; Roberts, Michael J.; Mutnick, Daniel; Woodmansee, David H.; Hollenbeck, Thomas; Gordon, Perry; Chang, Jonathan; Tuntland, Tove; Tumanut, Christine; Li, Jun; Harris, Jennifer L.; Karanewsky, Donald S. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5107 - 5111

443-69-6 ~% 769965-95-9

文献：Tully, David C.; Liu, Hong; Chatterjee, Arnab K.; Alper, Phil B.; Williams, Jennifer A.; Roberts, Michael J.; Mutnick, Daniel; Woodmansee, David H.; Hollenbeck, Thomas; Gordon, Perry; Chang, Jonathan; Tuntland, Tove; Tumanut, Christine; Li, Jun; Harris, Jennifer L.; Karanewsky, Donald S. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5107 - 5111

522612-15-3 ~% 769965-95-9

文献：Tully, David C.; Liu, Hong; Chatterjee, Arnab K.; Alper, Phil B.; Williams, Jennifer A.; Roberts, Michael J.; Mutnick, Daniel; Woodmansee, David H.; Hollenbeck, Thomas; Gordon, Perry; Chang, Jonathan; Tuntland, Tove; Tumanut, Christine; Li, Jun; Harris, Jennifer L.; Karanewsky, Donald S. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 19 p. 5107 - 5111

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