88124-27-0

• 常用中文名：依他西平
• 常用英文名：etazepine
• CAS号：88124-27-0
• 分子式：C₁₇H₁₇NO₂
• 分子量：267.32200
• 发布时间：2018-03-26 08:00:00
• 更新时间：2025-09-13 17:35:32

名称

• 中文名: 依他西平
• 英文名: 11-ethoxy-5-methyl-11H-benzo[c][1]benzazepin-6-one
• 英文别名: Etazepine; Etazepinum [Latin]; 5,6-Dihydro-5-methyl-11-ethoxy-11H-dibenzo(b,e)azepin-6-one; Etazepina [Spanish]; 6H-Dibenzo(b,e)azepin-6-one,5,11-dihydro-11-ethoxy-5-methyl; Etazepine [INN]; 5-methyl-11-ethoxy-5,6-dihydro-11H-dibenzo(b,e) azepine-6-one; EINECS 289-386-1; Etazepinum; 5,11-Dihydro-11-ethoxy-5-methyl-6H-dibenzo(b,e)azepin-6-one

物化性质

• 密度: 1.19g/cm3
• 沸点: 403.2ºC at 760 mmHg
• 分子式: C₁₇H₁₇NO₂
• 分子量: 267.32200
• 闪点: 197.7ºC
• 精确质量: 267.12600
• PSA: 29.54000
• LogP: 3.46750
• 折射率: 1.619

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HO4965000 CHEMICAL NAME : 6H-Dibenzo(b,e)azepin-6-one, 5,11-dihydro-11-ethoxy-5-methyl- CAS REGISTRY NUMBER : 88124-27-0 LAST UPDATED : 199706 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H17-N-O2 MOLECULAR WEIGHT : 267.35 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,475,1989 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1653 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 39,475,1989

安全

• 海关编码: 2933990090

合成路线

24391-82-0 64-17-5 ~84% 88124-27-0

文献：Pestellini; Viti; Nannicini; Borsini; Furio European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 473 - 476

24391-81-9 ~% 88124-27-0

文献：Pestellini; Viti; Nannicini; Borsini; Furio European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 473 - 476

上下游产品

上游产品  3
24391-82-0 64-17-5 24391-81-9
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%