481-46-9

481-46-9结构式

中文名	银杏素
英文名	ginkgetin
中文别名	银杏双黄酮白果双黄酮
英文别名	7,4'-di-O-methylamentoflavone Amentoflavone 7,4'-dimethyl ether 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)- 5,7-Dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one 4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)- ginkgetin 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one

描述	银杏双黄酮(Ginkgetin)是一种天然的双类黄酮,从银杏叶中分离,抗炎和抗癌生物活性。
相关类别	信号通路 >> 其他 >> 其他天然产物 >> 黄酮类化合物研究领域 >> 炎症/免疫
参考文献	[1]. Son JK, et al. Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. Biol Pharm Bull. 2005 Dec;28(12):2181-4. [2]. Jeon YJ, et al. Ginkgetin inhibits the growth of DU-145 prostate cancer cells through inhibition of STAT3 activity. Cancer Sci. 2015 Jan 22. doi: 10.1111/cas.12608. [3]. You OH, et al. Ginkgetin induces apoptosis via activation of caspase and inhibition of survival genes in PC-3 prostate cancer cells. Bioorg Med Chem Lett. 2013 May 1;23(9):2692-5. [4]. Kwak WJ, et al. Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. Planta Med. 2002 Apr;68(4):316-21.

135159-04-5

~96%

481-46-9

文献：Muller, Dominique; Fleury, Jean-Pierre Tetrahedron Letters, 1991 , vol. 32, # 20 p. 2229 - 2232

3754-52-7

481-46-9

文献：Muller, Dominique; Fleury, Jean-Pierre Tetrahedron Letters, 1991 , vol. 32, # 20 p. 2229 - 2232

135159-00-1

481-46-9

文献：Muller, Dominique; Fleury, Jean-Pierre Tetrahedron Letters, 1991 , vol. 32, # 20 p. 2229 - 2232