635319-09-4

• 常用中文名：(3R,4R)-3-羟基-4-(羟甲基)吡咯烷-1-羧酸叔丁酯
• 常用英文名：(3R,4R)-tert-Butyl 3-Hydroxy-4-(hydroxyMethyl)pyrrolidine-1-carboxylate
• CAS号：635319-09-4
• 分子式：C₁₀H₁₉NO₄
• 分子量：217.26200
• 发布时间：2016-07-11 09:39:20
• 更新时间：2024-01-07 11:39:20

名称

• 中文名: (3R,4R)-3-羟基-4-(羟甲基)吡咯烷-1-羧酸叔丁酯
• 英文名: 2-Methyl-2-propanyl (3R,4R)-3-hydroxy-4-(hydroxymethyl)-1-pyrroli dinecarboxylate
• 英文别名: N-tert-butoxycarbonyl-(3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine; tert-butyl (3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate; (3R,4R)-1-tert-butoxycarbonyl-3-hydroxy-4-(hydroxymethyl)pyrrolidine; (3R,4R)-N-tert-butoxycarbonyl-3-hydroxy-4-hydroxymethylpyrrolidine; (3R,4R)-tert-butyl 3-hydroxy-4-(hydroxymethyl)pyrrolidine-1-carboxylate; tert-butyl trans(+-)-4-amino-3-hydroxypiperidine-1-carboxylate; (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol; tert-butyl (3R*,4R*)-4-amino-3-hydroxy-piperidine-1-carboxylate; (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidin-1-N-carboxylic acid tert-butyl ester

物化性质

• 分子式: C₁₀H₁₉NO₄
• 分子量: 217.26200
• 精确质量: 217.13100
• PSA: 70.00000
• LogP: 0.14440
• 储存条件: 室温

合成路线

635319-08-3 ~92% 635319-09-4

文献：ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY; INDUSTRIAL RESEARCH LIMITED Patent: WO2004/18496 A1, 2004 ; Location in patent: Page 23-24 ; WO 2004/018496 A1

253129-03-2 24424-99-5 ~99% 635319-09-4

文献：INDUSTRIAL RESEARCH LIMITED; ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY Patent: WO2007/69923 A1, 2007 ; Location in patent: Page/Page column 18; 21 ;

24424-99-5 267421-93-2 ~% 635319-09-4

文献：INDUSTRIAL RESEARCH LIMITED Patent: WO2005/118532 A1, 2005 ; Location in patent: Page/Page column 23 ;

849935-77-9 ~% 635319-09-4

文献：Clinch, Keith; Evans, Gary B.; Fleet, George W. J.; Furneaux, Richard H.; Johnson, Stephen W.; Lenz, Dirk H.; Mee, Simon P. H.; Rands, Peter R.; Schramm, Vern L.; Taylor Ringia, Erika A.; Tyler, Peter C. Organic and Biomolecular Chemistry, 2006 , vol. 4, # 6 p. 1131 - 1139

24424-99-5 ~% 635319-09-4

文献：Clinch, Keith; Evans, Gary B.; Fleet, George W. J.; Furneaux, Richard H.; Johnson, Stephen W.; Lenz, Dirk H.; Mee, Simon P. H.; Rands, Peter R.; Schramm, Vern L.; Taylor Ringia, Erika A.; Tyler, Peter C. Organic and Biomolecular Chemistry, 2006 , vol. 4, # 6 p. 1131 - 1139

253129-03-2 ~% 635319-09-4

文献：CALLAGHAN INNOVATION RESEARCH LIMITED; EVANS, Gary Brian; KELLY, Peter Michael; TYLER, Peter Charles Patent: WO2014/73989 A1, 2014 ;