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| 中文名 | 2-氨基茚满-2-甲酸 |
|---|---|
| 英文名 | 2-amino-1,3-dihydroindene-2-carboxylic acid |
| 中文别名 |
2-氨基-2,3-二氢茚基乙酸
2-氨基-2,3-二氢-1H-茚-2-羧酸 |
| 英文别名 |
2-Amino-2-indancarboxylicacid
2-amino-2,3-dihydro-1H-indene-2-carboxylic acid 2-amino-indan-2-carboxylic acid MFCD01456491 2-Amino-indan-2-carbonsaeure 1H-Indene-2-carboxylic acid, 2-amino-2,3-dihydro- 2-Aminoindane-2-carboxylic acid 2,3-dihydroindene-2-amino-2-carboxylic acid 2-Amino-2-indanecarboxylic acid 2-Aminoindan-2-carboxylic Acid 2-amino-2,3-dihydro-1H-indene-2-carboxylicacid |
| 密度 | 1.3±0.1 g/cm3 |
|---|---|
| 沸点 | 357.1±42.0 °C at 760 mmHg |
| 熔点 | 298ºC |
| 分子式 | C10H11NO2 |
| 分子量 | 177.200 |
| 闪点 | 169.8±27.9 °C |
| 精确质量 | 177.078979 |
| PSA | 63.32000 |
| LogP | 1.45 |
| 外观性状 | 白色固体 |
| 蒸汽压 | 0.0±0.8 mmHg at 25°C |
| 折射率 | 1.619 |
| 储存条件 | Store at 0°C |
Synonym:None known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air). Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 27473-62-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: white Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 298 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Soluble. Specific Gravity/Density: Molecular Formula: C10H11NO2 Molecular Weight: 177.20 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, dust generation, moisture, excess heat. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 27473-62-7 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Amino-2-Indanecarboxylic Acid - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 37/39 Wear suitable gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 27473-62-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 27473-62-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 27473-62-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危害码 (欧洲) | Xi |
|---|---|
| 风险声明 (欧洲) | 36/37/38 |
| 安全声明 (欧洲) | 26-36/37/39-45 |
| 海关编码 | 2922499990 |
|
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| 文献：Schiller; Weltrowska; Nguyen; Lemieux; Chung; Marsden; Wilkes Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3125 - 3132 |
|
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| 文献：PROPHARMACON, INC. Patent: WO2006/22955 A2, 2006 ; Location in patent: Page/Page column 78-79 ; |
|
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| 文献：Grouiller; Nioche; Barailler; et al. European Journal of Medicinal Chemistry, 1980 , vol. 15, # 2 p. 139 - 146 |
|
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| 文献：Belokon, Yuri N.; Kochetkov, Konstantin A.; Borkin, Dmitry A. Mendeleev Communications, 2003 , vol. 13, # 3 p. 132 - 134 |
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| 文献：Gagnon; Boivin Canadian Journal of Research, Section B: Chemical Sciences, 1948 , vol. 26, p. 503,509 |
| 上游产品 5 | |
|---|---|
| 下游产品 4 | |
| 海关编码 | 2922499990 |
|---|---|
| 中文概述 | 2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0% |
| 申报要素 | 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装 |
| 监管条件 | A.入境货物通关单 B.出境货物通关单 |
| 检验检疫 | P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验 |
| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
