74037-56-2

• 常用中文名：N-(2-methoxyethyl)-5-nitro-pyridin-2-amine
• 常用英文名：N-(2-methoxyethyl)-5-nitro-pyridin-2-amine
• CAS号：74037-56-2
• 分子式：C₈H₁₁N₃O₃
• 分子量：197.19100
• 发布时间：2017-10-04 13:01:26
• 更新时间：2024-01-15 13:17:45

名称

• 英文名: N-(2-methoxyethyl)-5-nitropyridin-2-amine
• 英文别名: Pyridine,2-((2-methoxyethyl)amino)-5-nitro; 2-((2-Methoxyethyl)amino)-5-nitropyridine; 2-Pyridinamine,N-(2-methoxyethyl)-5-nitro

物化性质

• 密度: 1.286g/cm3
• 沸点: 357.7ºC at 760 mmHg
• 分子式: C₈H₁₁N₃O₃
• 分子量: 197.19100
• 闪点: 170.1ºC
• 精确质量: 197.08000
• PSA: 79.97000
• LogP: 1.64430
• 折射率: 1.586

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UT5100000 CHEMICAL NAME : Pyridine, 2-((2-methoxyethyl)amino)-5-nitro- CAS REGISTRY NUMBER : 74037-56-2 LAST UPDATED : 197901 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H11-N3-O3 MOLECULAR WEIGHT : 197.22 WISWESSER LINE NOTATION : T6NJ BM2O1 ENW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03679

合成路线

4548-45-2 109-85-3 ~84% 74037-56-2

文献：Gruenenthal GmbH; FRANK, Robert; Christoph, Thomas; Lesch, Bernhard; Lee, Jeewoo Patent: US2013/29961 A1, 2013 ; Location in patent: Paragraph 0726 ;

109-85-3 ~% 74037-56-2

文献：Yun, Weiya; Ahmad, Mushtaq; Chen, Yingsi; Gillespie, Paul; Conde-Knape, Karin; Kazmer, Sonja; Li, Shiming; Qian, Yimin; Taub, Rebecca; Wertheimer, Stanley J.; Whittard, Toni; Bolin, David Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7205 - 7209

5418-51-9 ~% 74037-56-2

文献：GRÜNENTHAL GMBH; FRANK, Robert; BAHRENBERG, Gregor; CHRISTOPH, Thomas; LESCH, Bernhard Patent: WO2013/13815 A1, 2013 ; WO 2013/013815 A1

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