168683-02-1

• 常用中文名：(1S,4R)-4-[[叔丁氧羰基]氨基]-2-环戊烯-1-羧酸甲酯
• 常用英文名：4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-2-CYCLOPENTENE-1-CARBOXYLIC ACID METHYL ESTER
• CAS号：168683-02-1
• 分子式：C₁₂H₁₉NO₄
• 分子量：241.284
• 发布时间：2018-12-03 17:59:17
• 更新时间：2024-01-02 17:45:46

名称

• 中文名: 4-[[(1,1-二甲基乙氧基)羰基]氨基]-2-环戊烯-1-羧酸甲酯
• 英文名: (1S,4R)-Methyl 4-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylate
• 中文别名: (1S,4R)-4-(叔丁氧羰基氨基)-环戊-2-烯基-1-甲酸甲酯; 帕拉米韦中间体1
• 英文别名: Methyl (1S,4R)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylate; 2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1S,4R)-; Methyl (1S,4R)-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-2-cyclopentene-1-carboxylate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic acid methyl ester

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 331.2±42.0 °C at 760 mmHg
• 分子式: C₁₂H₁₉NO₄
• 分子量: 241.284
• 闪点: 154.1±27.9 °C
• 精确质量: 241.131409
• PSA: 64.63000
• LogP: 1.58
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.489
• 储存条件: 室温，干燥

合成路线

24424-99-5 229613-83-6 ~10% 168683-02-1

文献：Kuraray Co., Ltd. Patent: EP1334969 A1, 2003 ;

151792-53-9 ~60% 168958-19-8 168683-02-1

文献：DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; LLOYD, Richard; PETERSON, Justine, Ann; JACKSON, Mark Patent: WO2011/3061 A2, 2011 ; Location in patent: Page/Page column 13-14 ;

79200-56-9 ~% 168683-02-1

文献：Chand; Montgomery; Kotian; Dehghani; El-Kattan; Lin; Hutchison; Babu; Bantia; Elliott Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4379 - 4392

4157-02-2 ~% 168683-02-1

文献：Trost, Barry M.; Stenkamp, Dirk; Pulley, Shon R. Chemistry--A European Journal, 1995 , vol. 1, # 8 p. 568 - 572

24424-99-5 ~% 168683-02-1

文献：Trost, Barry M.; Stenkamp, Dirk; Pulley, Shon R. Chemistry--A European Journal, 1995 , vol. 1, # 8 p. 568 - 572

173464-46-5 ~% 168683-02-1

文献：Trost, Barry M.; Stenkamp, Dirk; Pulley, Shon R. Chemistry--A European Journal, 1995 , vol. 1, # 8 p. 568 - 572

24424-99-5 138923-03-2 ~% 168683-02-1

文献：Chand; Montgomery; Kotian; Dehghani; El-Kattan; Lin; Hutchison; Babu; Bantia; Elliott Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4379 - 4392

102579-71-5 ~% 168683-02-1

文献：Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B. Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

186581-53-3 151907-79-8 ~% 168683-02-1

文献：Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B. Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

上下游产品

上游产品  8
24424-99-5 151792-53-9 79200-56-9 4157-02-2
138923-03-2 102579-71-5 186581-53-3 151907-79-8
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