2347-80-0

• 常用中文名：甲磺酸硫达唑嗪
• 常用英文名：Thioproperazine dimesylate
• CAS号：2347-80-0
• 分子式：C₂₄H₃₈N₄O₈S₄
• 分子量：638.84100
• 发布时间：2018-05-18 08:00:00
• 更新时间：2024-01-22 06:51:01

名称

• 中文名: 甲磺酸硫达唑嗪
• 英文名: N,N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide,methanesulfonic acid
• 中文别名: N,N-二甲基-10-[3-(4-甲基哌嗪-1-基)丙基]吩噻嗪-2-磺酰胺甲磺酸盐
• 英文别名: 10-[3-(4-methyl-piperazin-1-yl)-propyl]-10H-phenothiazine-2-sulfonic acid dimethylamide,bis-methanesulfonate; Mageptyl; thioproperazine dimethanosulphonate; Thioproperazine dimesylate; Thioperazine methanesulfate; thioproperazine mesylate; Thioproperazindimethansulfat; Majeptil; Thioproperazine dimesilate; Thioperazine dimethanesulfonate; Thioproperazine mesilate; Thioproperazine dimethanesulfonate; thioproperazine dimethansulfonate

物化性质

• 沸点: 612.2ºC at 760mmHg
• 熔点: 218-222ºC
• 分子式: C₂₄H₃₈N₄O₈S₄
• 分子量: 638.84100
• 精确质量: 638.15700
• PSA: 206.28000
• LogP: 5.36830
• 蒸汽压: 6.32E-15mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SP5425000 CHEMICAL NAME : Phenothiazine-2-sulfonamide, N,N-dimethyl-10-(3-(4-methyl-1-piperazinyl)propyl)-, dimethanesulfonate CAS REGISTRY NUMBER : 2347-80-0 LAST UPDATED : 199512 DATA ITEMS CITED : 13 MOLECULAR FORMULA : C22-H30-N4-O2-S2.2C-H4-O3-S MOLECULAR WEIGHT : 638.90 WISWESSER LINE NOTATION : T C666 BN ISJ ESWN1&1 B3- AT6N DNTJ D1 &OSW1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 59 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 115 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 70 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TEST SYSTEM : Rodent - mouse DOSE/DURATION : 5 mg/kg REFERENCE : CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 9(5),14,1975

安全

• 危害码 (欧洲): Xn