7253-19-2

• 常用中文名：5-O-(4-甲基苯基磺酰基)胸腺嘧啶脱氧核苷
• 常用英文名：Thymidine,5'-(4-methylbenzenesulfonate)
• CAS号：7253-19-2
• 分子式：C₁₇H₂₀N₂O₇S
• 分子量：396.41500
• 发布时间：2018-12-27 22:01:09
• 更新时间：2024-01-09 12:54:14

名称

• 中文名: 5-O-(4-甲基苯基磺酰基)胸腺嘧啶脱氧核苷
• 英文名: 5'-o-(4-methylphenylsulphonyl)thymidine
• 英文别名: 5'-O-tosyl-2'-deoxythymidine; thymidine 5'-p-toluenesulfonate; 5'-O-p-toluenesulfonylthymidine; Thymidine 5'-tosylate; 5'-O-TOLUOLSULFONYL-THYMIDINE; 5'-O-p-tolylsulfonylthymidine; 5'-toluenesulfonylthymidine; 5'-O-p-tosyl-thymidine

物化性质

• 密度: 1.425 g/cm3
• 分子式: C₁₇H₂₀N₂O₇S
• 分子量: 396.41500
• 精确质量: 396.09900
• PSA: 136.07000
• LogP: 1.28810
• 折射率: 1.597

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XP2085000 CHEMICAL NAME : Thymidine, 5'-O-(p-toluenesulfonyl)- CAS REGISTRY NUMBER : 7253-19-2 LAST UPDATED : 199707 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H20-N2-O7-S MOLECULAR WEIGHT : 396.45 WISWESSER LINE NOTATION : T6NVMVJ E1 A- BT5OTJ DQ E1SWR D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00221

安全

• 危害码 (欧洲): Xi: Irritant;

合成路线

98-59-9 50-89-5 ~90% 7253-19-2

文献：Wang, Hua; Cheng, Changmei; Zheng, Hongchao; Liu, Xiaohong; Fang, Chang; Xu, Shanshan; Zhao, Yufen Chemistry Letters, 2005 , vol. 34, # 3 p. 432 - 433

129801-99-6 ~% 7253-19-2

文献：Journal of Organic Chemistry, , vol. 52, # 9 p. 1794 - 1801

98-59-9 ~% 7253-19-2

文献：Journal of Organic Chemistry, , vol. 52, # 9 p. 1794 - 1801

40733-27-5 ~% 7253-19-2

文献：Journal of Organic Chemistry, , vol. 52, # 9 p. 1794 - 1801

50-89-5 ~65% 7253-19-2

文献：Jahn-Hofmann, Kerstin; Engels, Joachim W. Helvetica Chimica Acta, 2004 , vol. 87, # 11 p. 2812 - 2828

98-59-9 50-89-5 ~% 63914-08-9 7253-19-2

文献：Journal of Chemical Research, Miniprint, , # 1 p. 301 - 326

上下游产品

上游产品  4
98-59-9 50-89-5 129801-99-6 40733-27-5
下游产品  8
59495-21-5 15425-09-9 19316-85-9 25152-20-9
7150-83-6 75191-50-3 84364-97-6 5983-11-9