| 中文名 | 磷酸可待因 |
|---|---|
| 英文名 | codeine phosphate |
| 英文别名 |
CODEINEPHOSPHATE,USP
CODEINIUM PHOSPHATE HEMIHYDRATE Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-, phosphate, hydrate (2:2:1) (salt) MORPHINE-3-METHYL ETHER HEMIHYDRATE Codein phosphate hemihydrate N-METHYLNORCODEINE HEMIHYDRATE (5α,6α)-3-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol phosphate hydrate (2:2:1) |
| 沸点 | 462ºC at 760 mmHg |
|---|---|
| 熔点 | 157.5ºC |
| 分子式 | C18H26NO8P |
| 分子量 | 812.734 |
| 闪点 | 233.2ºC |
| 精确质量 | 812.268616 |
| PSA | 138.73000 |
| LogP | 0.44610 |
|
Section 1. Chemical Product and Company Identification Codeine phosphateCatalog Common Name/ Number(s). Trade Name CAS#41444-62-6 Manufacturer
RTECSQD1310000 SPECTRUM CHEMICAL MFG. CORP. TSCATSCA 8(b) inventory: Codeine phosphate Commercial Name(s)Not available. CI# Not available. SynonymNot available. IN CASE OF EMERGENCY Not available. Chemical Name Chemical FamilyNot available.CALL (310) 516-8000 C18H21NO3.H3PO4.1/2H20 Chemical Formula SPECTRUM CHEMICAL MFG. CORP. Section 2.Composition and Information on Ingredients Exposure Limits TWA (mg/m3)STEL (mg/m3) CEIL (mg/m3) NameCAS #% by Weight 1) Codeine phosphate41444-62-6100 Toxicological DataCodeine phosphate: on IngredientsORAL (LD50):Acute: 85 mg/kg [Rat]. 237 mg/kg [Mouse]. 654 mg/kg [Guinea pig]. Section 3. Hazards Identification Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant). Slightly hazardous in case of skin contact (permeator). Severe over-exposure can result in death. Potential Chronic HealthCARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. Effects TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Codeine phosphate Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention. Skin ContactAfter contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Serious Skin ContactWash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention. InhalationAllow the victim to rest in a well ventilated area. Seek immediate medical attention. Serious InhalationEvacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention. IngestionDo not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Serious Ingestion Not available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Flash PointsNot available. Flammable LimitsNot available. Products of CombustionThese products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), phosphates. Fire Hazards in Presence of Not available. Various Substances Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. of Various Substances SMALL FIRE: Use DRY chemical powder. Fire Fighting Media and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Not available. Special Remarks on Fire Hazards Special Remarks on Explosion Not available. Hazards Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Large SpillUse a shovel to put the material into a convenient waste disposal container. Codeine phosphate Section 7. Handling and Storage PrecautionsKeep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes StorageKeep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate locked safety storage cabinet or room. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Powdered solid.)OdorOdorless. TasteNot available. 406.37 g/mole Molecular Weight ColorWhite. pH (1% soln/water)Not available. Not available. Boiling Point Melting PointNot available. Not available. Critical Temperature Specific GravityNot available. Vapor PressureNot applicable. Vapor DensityNot available. VolatilityNot available. Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Not available. Ionicity (in Water) Dispersion PropertiesSee solubility in water, methanol. SolubilitySoluble in cold water. Partially soluble in methanol. Insoluble in diethyl ether. Codeine phosphate Section 10. Stability and Reactivity Data The product is stable. Stability Instability TemperatureNot available. Not available. Conditions of Instability Not available. Incompatibility with various substances CorrosivityNon-corrosive in presence of glass. Special Remarks onNot available. Reactivity Special Remarks onNot available. Corrosivity PolymerizationNo. Section 11. Toxicological Information Routes of EntryEye contact. Inhalation. Ingestion. Toxicity to AnimalsAcute oral toxicity (LD50): 85 mg/kg [Rat]. Chronic Effects on Humans Not available. Other Toxic Effects onHazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant). HumansSlightly hazardous in case of skin contact (permeator). Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherMay Be Habit Forming Toxic Effects on Humans Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are more toxic. Toxicity of the Products of Biodegradation Special Remarks on theNot available. Products of Biodegradation Codeine phosphate Section 13. Disposal Considerations Waste Disposal Section 14. Transport Information DOT ClassificationCLASS 6.1: Poisonous material. : Alkaloid Salt, Solid, n.o.s.(Codeine Phosphate) : UN1544 PG: III Identification Not available. Special Provisions for Transport DOT (Pictograms) HARMFUL STOW AWAY FROM FOODSTUFFS 6 Section 15. Other Regulatory Information and Pictograms TSCA 8(b) inventory: Codeine phosphate Federal and State Regulations California Proposition 65 Warnings Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC). Other Classifications DSCL (EEC)R25- Toxic if swallowed. R36/37/38- Irritating to eyes, respiratory system and skin. Health Hazard HMIS (U.S.A.)3 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 3 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) 6 Codeine phosphate ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 危险品运输编码 | UN 1544PSN2 6.1 / PGIII |
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