179463-85-5

• 常用中文名：(3R,4S)-4-(4-氟苯基)-3-哌啶甲醇
• 常用英文名：(3R,4R)-4-(4-Fluorophenyl)-3-piperidinemethanol
• CAS号：179463-85-5
• 分子式：C₁₃H₁₈FNO
• 分子量：223.28700
• 发布时间：2018-11-24 13:22:13
• 更新时间：2025-08-25 11:28:44

名称

• 中文名: (3R,4S)-4-(4-氟苯基)-3-哌啶甲醇
• 英文名: [(3R,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinyl]methanol
• 英文别名: trans-4-(p-fluorophenyl)-3-piperidinecarbinol; (3R,4S)-(+)-4-(4'-fluorophenyl)-3-hydroxymethylpiperidine; 4-(4-CHLOROPHENYL)CYCLOHENXANECARBOXYLICACID; (3R,4R)-4-(4-Fluorophenyl)-3-piperidinemethanol; (3SR,4RS)-trans-4-(4-fluorophenyl)-3-hydroxymethylpiperidine; (1r,4r)-4-(4-Chlorophenyl)cyclohexanecarboxylic acid; (E)-4-(4-chlorophenyl)-cyclohexanecarboxylic acid; trans-4-(4-chlorophenyl)cyclohexanecarboxylic acid; rel-[(3R,4S)-4-(4-fluorophenyl)piperidin-3-yl]methanol; trans-4-(4-chlorophenyl)cyclohexane-1-carboxylic acid; 4-(p-Chlorophenyl)-1-cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid,4-(4-chlorophenyl)-,trans; TRANS-4-(4-CHLOROPHENYL)CYCLOHEXANECARBOXYLIC; trans-4-(4'-Fluorophenyl)-3-hydroxymethylpiperidine

物化性质

• 密度: 1.092g/cm3
• 沸点: 300.3ºC at 760 mmHg
• 分子式: C₁₃H₁₈FNO
• 分子量: 223.28700
• 闪点: 135.4ºC
• 精确质量: 223.13700
• PSA: 23.47000
• LogP: 1.79120
• 蒸汽压: 0.000504mmHg at 25°C
• 折射率: 1.518

合成路线

392328-27-7 ~88% 179463-85-5

文献：De Gonzalo; Brieva; Sanchez; Bayod; Gotor Journal of Organic Chemistry, 2001 , vol. 66, # 26 p. 8947 - 8953

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