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3223-07-2生产厂家

3223-07-2价格

3223-07-2

3223-07-2结构式
3223-07-2结构式

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中文名 左旋苯丙氨酸氮芥盐酸盐
英文名 Melphalan hydrochloride
中文别名 盐酸美法仑
盐酸美法仑
(S)-3-[4-[双(2-氯乙基)氨基]苯基]丙氨酸盐酸盐
英文别名 DL-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, hydrochloride
DL-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, monohydrochloride
L-phenylalanine, 4-[bis(2-chloroethyl)amino]-, monohydrochloride
4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1)
acide (2S)-2-amino-3-{4-[bis(2-chloroéthyl)amino]phényl}propanoïque chlorhydrate
DL-Phenylalanine, 4-(bis(2-chloroethyl)amino)-, monohydrochloride (9CI)
L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-, monohydrochloride (9CI)
(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid hydrochloride
4-(Bis(2-chloroethyl)amino)-L-phenylalanine Monohydrochloride
3-(p-(Bis(β-chloroethyl)amino)phenyl)-D,L-alanine hydrochloride
4-(Bis(2-chloroethyl)amino)-DL-phenylalanine hydrochloride
Melphalan Hydrochloride,Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
(2S)-2-Amino-3-{4-[bis(2-chlorethyl)amino]phenyl}propansäurehydrochlorid
3-[p-[Bis(β-chloroethyl)amino]phenyl]-D,L-alanine, hydrochloride
4-[bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride
L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
3-(p-(Bis(2-chloroethyl)amino)phenyl)-DL-alanine hydrochloride
DL-Alanine, 3-(p-[bis(2-chloroethyl)amino]phenyl)-, hydrochloride
L-Alanine, 3-(p-[bis(2-chloroethyl)amino]phenyl)-, hydrochloride
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine Hydrochloride
沸点 473.1ºC at 760mmHg
分子式 C13H19Cl3N2O2
分子量 341.661
闪点 239.9ºC
精确质量 340.051208
PSA 66.56000
LogP 3.42730
外观性状 固体
储存条件 库房通风低温干燥,与食品原料分开存放

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY4025000
CHEMICAL NAME :
Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, monohydrochloride, L-
CAS REGISTRY NUMBER :
3223-07-2
LAST UPDATED :
199706
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C13-H18-Cl2-N2-O2.Cl-H
MOLECULAR WEIGHT :
341.69
WISWESSER LINE NOTATION :
QVYZ1R DN2G2G &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
1200 ug/kg/5D-I
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
REFERENCE :
CCROBU Cancer Chemotherapy Reports, Part 1. (Washington, DC) V.52(6)-59, 1968-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 57,369,1973
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
430 ug/kg
TOXIC EFFECTS :
Blood - leukopenia Blood - thrombocytopenia Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
430 ug/kg
TOXIC EFFECTS :
Blood - leukopenia Blood - agranulocytosis Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 ug/kg/4W
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966

危害码 (欧洲) Xn
海关编码 2922499990
海关编码 2922499990
中文概述 2922499990 其他氨基酸及其酯及它们的盐(含有一种以上含氧基的除外). 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件 A.入境货物通关单 B.出境货物通关单
检验检疫 P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%