4055-40-7

• 常用中文名：MITOMYCIN B
• 常用英文名：MITOMYCIN B
• CAS号：4055-40-7
• 分子式：C₁₆H₁₉N₃O₆
• 分子量：349.339
• 发布时间：2016-05-09 01:57:08
• 更新时间：2025-09-13 18:05:00

名称

• 英文名: mitomycin B
• 英文别名: Mitomycin B 0nnDiscontinued; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-,8-carbamate; Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-, (1aS,8R,8aR,8bS)-; MITOMYCIN B; [(1aS,8R,8aR,8bS)-8a-Hydroxy-6-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate; CID4209

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 606.6±55.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉N₃O₆
• 分子量: 349.339
• 闪点: 320.6±31.5 °C
• 精确质量: 349.127380
• PSA: 122.17000
• LogP: 0.98
• 蒸汽压: 0.0±3.9 mmHg at 25°C
• 折射率: 1.675

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CN0875000 CAS REGISTRY NUMBER : 4055-40-7 LAST UPDATED : 199806 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C16-H19-N3-O6 MOLECULAR WEIGHT : 349.38 WISWESSER LINE NOTATION : T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KO1 L1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Mammal - species unspecified Lymphocyte DOSE/DURATION : 60 umol/L REFERENCE : CJBIAE Canadian Journal of Biochemistry. (Ontario, Canada) V.42-60, 1964-82. For publisher information, see CJBBDU. Volume(issue)/page/year: 56,296,1978

合成路线

92056-68-3 ~% 4055-40-7

文献：Danishefsky; Ciufolini Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6424 - 6425

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