4055-40-7

4055-40-7 structure
4055-40-7 structure
  • Name: MITOMYCIN B
  • Chemical Name: mitomycin B
  • CAS Number: 4055-40-7
  • Molecular Formula: C16H19N3O6
  • Molecular Weight: 349.339
  • Create Date: 2016-05-09 01:57:08
  • Modify Date: 2024-01-08 18:09:51

Name mitomycin B
Synonyms Mitomycin B 0nnDiscontinued
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-,8-carbamate
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-, (1aS,8R,8aR,8bS)-
MITOMYCIN B
[(1aS,8R,8aR,8bS)-8a-Hydroxy-6-methoxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
CID4209
Density 1.6±0.1 g/cm3
Boiling Point 606.6±55.0 °C at 760 mmHg
Molecular Formula C16H19N3O6
Molecular Weight 349.339
Flash Point 320.6±31.5 °C
Exact Mass 349.127380
PSA 122.17000
LogP 0.98
Vapour Pressure 0.0±3.9 mmHg at 25°C
Index of Refraction 1.675

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CN0875000
CAS REGISTRY NUMBER :
4055-40-7
LAST UPDATED :
199806
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C16-H19-N3-O6
MOLECULAR WEIGHT :
349.38
WISWESSER LINE NOTATION :
T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KO1 L1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
60 umol/L
REFERENCE :
CJBIAE Canadian Journal of Biochemistry. (Ontario, Canada) V.42-60, 1964-82. For publisher information, see CJBBDU. Volume(issue)/page/year: 56,296,1978

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4055-40-7 structure

4055-40-7

Literature: Danishefsky; Ciufolini Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6424 - 6425
Precursor  0

DownStream  3